What is Epidocin used for?

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Epidocin (Valethemate Bromide)

Primary Indication

Epidocin is used to accelerate cervical dilatation during labor, thereby shortening the first stage of labor in both primigravidas and multiparous women. 1

Mechanism and Clinical Application

Valethemate bromide (marketed as Injection Epidosin) functions as an antispasmodic agent that facilitates cervical dilatation during uncomplicated labor. 1

Evidence for Efficacy

  • A study of 500 patients (250 primigravidas and 250 multiparas) demonstrated that Epidosin significantly reduced the duration of the first stage of labor in both groups without major side effects. 1
  • The medication can be safely administered under nursing staff supervision during active labor. 1

Patient Selection

Appropriate Candidates

  • Primigravidas experiencing uncomplicated labor 1
  • Multiparous women with uncomplicated labor 1
  • Patients with cervical dystocia that may prolong labor and adversely affect fetomaternal wellbeing 1

Clinical Context

The importance of addressing cervical dystocia is critical, as prolonged labor can negatively impact both maternal and fetal outcomes. 1

Administration Considerations

  • The medication is administered as an injection during active labor 1
  • Supervision by nursing staff is required during administration 1
  • The drug is specifically indicated for uncomplicated labor scenarios 1

Safety Profile

The available evidence indicates that Epidosin can be used safely without major side effects when administered appropriately in the labor setting. 1 However, its use should be restricted to uncomplicated labor cases under proper medical supervision. 1

References

1
Research

VALETHEMATE BROMIDE AND CERVICAL DILATATION.

Medical journal, Armed Forces India, 1999

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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