When to Use Levosalbutamol (Levalbuterol) Inhaler
Use your levosalbutamol inhaler for quick relief of acute asthma or COPD symptoms (wheezing, shortness of breath, chest tightness) at a dose of 2 puffs every 4-6 hours as needed, or 15-30 minutes before exercise to prevent exercise-induced bronchospasm. 1, 2
Primary Indications for Use
Acute Symptom Relief (Rescue Therapy)
- Take 2 puffs (45 mcg/puff) when you experience sudden breathing difficulty, wheezing, chest tightness, or cough 1, 3
- The medication should provide relief within minutes and last 4-6 hours 4
- You may repeat dosing every 4-6 hours as needed, but do not exceed 8 puffs in 24 hours 3
Exercise-Induced Bronchospasm Prevention
- Take 2 puffs 15-30 minutes before planned physical activity 1, 2, 3
- This provides protection for approximately 4-5 hours, though duration may decrease with chronic regular use 1
Acute Exacerbations (Severe Symptoms)
- For moderate to severe breathing difficulty, take 4-8 puffs via MDI with spacer every 20 minutes for up to 3 doses 2, 3
- If symptoms persist after this initial treatment, seek immediate medical attention 5
Critical Warning Signs Requiring Medical Attention
Seek emergency care immediately if: 5
- You need to use your inhaler more frequently than every 4 hours
- Your symptoms worsen despite using the inhaler
- You experience no relief within 15-20 minutes of use
- You develop difficulty speaking in full sentences, altered mental status, or extreme fatigue
Important Usage Guidelines
Proper Technique
- Shake the inhaler well before each use 4
- Prime with 4 test sprays if using for the first time or if not used for more than 3 days 4
- Inhale slowly and deeply during actuation, then hold breath for 10 seconds 1
- Clean the plastic actuator weekly by running warm water through it for 30 seconds, then air-dry thoroughly overnight 4
Monitoring Your Asthma Control
- If you need levosalbutamol more than 2 days per week for symptom relief (excluding exercise prevention), your asthma is poorly controlled 1, 3
- This signals the need to start or adjust daily controller medications (inhaled corticosteroids) 1, 2
- Increasing frequency of use indicates worsening disease and requires physician evaluation 1, 4
Levosalbutamol vs. Racemic Albuterol
Levosalbutamol is the R-enantiomer of albuterol and provides comparable bronchodilation at half the milligram dose of racemic albuterol 2, 6, 7:
- 100 mcg levosalbutamol ≈ 200 mcg racemic albuterol in effectiveness 7
- Both have similar onset, duration, and peak effect 7, 8
- Levosalbutamol may have fewer beta-mediated side effects (tremor, tachycardia) at equivalent doses, though clinical significance remains debated 6, 9, 8
Common Side Effects to Expect
- Rapid heartbeat (tachycardia)
- Tremor or shakiness
- Headache
- Nervousness
These effects are generally mild with inhaled use and typically resolve as your body adjusts to the medication 1
Special Precautions
Use with caution if you have 4:
- Heart disease, high blood pressure, or irregular heart rhythms
- Diabetes (can raise blood sugar)
- Thyroid disorders
- Seizure disorders
Never use levosalbutamol as your only asthma medication if you have persistent symptoms - it is a rescue inhaler, not a controller medication 1, 3