How to manage chronic metatarsal pain in the greater toe?

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Last updated: November 25, 2025View editorial policy

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Management of Chronic Metatarsal Pain in the Greater Toe

For 8 months of metatarsal pain in the great toe, begin with conservative management including proper footwear modifications, NSAIDs, and custom orthotic devices for at least 3-6 months before considering surgical intervention. 1

Initial Diagnostic Approach

Obtain plain radiographs of the foot first to exclude structural abnormalities, arthritis, stress fractures, or bipartite sesamoids. 2, 3 This is the appropriate initial imaging for chronic foot pain of unknown etiology. 2

If radiographs are negative or equivocal and pain persists, proceed to MRI of the foot without IV contrast as the next imaging study. 2, 1 MRI is superior for evaluating:

  • Sesamoiditis (bone marrow edema in the hallucal sesamoid bones under the first metatarsophalangeal joint) 3
  • Stress fractures and occult fractures 2
  • Cartilage loss and subchondral bone changes in the first metatarsophalangeal or tarsometatarsal joints 1
  • Plantar plate injuries 2

Ultrasound is an acceptable alternative that allows dynamic examination and direct clinical correlation, with 90% sensitivity for detecting pathology. 4, 2

Conservative Treatment Protocol (First-Line for 3-6 Months)

Footwear Modifications

  • Use well-fitted walking shoes or athletic shoes that cushion the feet and redistribute pressure away from the metatarsal heads. 2
  • For bony deformities (hammertoes, prominent metatarsal heads, bunions), prescribe extra-wide or depth shoes. 2
  • For extreme deformities, custom-molded shoes may be necessary. 2

Orthotic Devices

  • Custom orthotic devices with metatarsal supports to redistribute excessive loading under the metatarsal heads. 2, 5
  • Dynamic impression insoles can reduce peak pressure by 46% and pressure-time integral by 49% compared to flat insoles, with significant pain reduction in metatarsalgia. 5

Pharmacologic Management

  • NSAIDs (such as naproxen 375-500 mg twice daily) for pain and inflammation control. 2, 1, 6
  • Naproxen has been shown to be effective for musculoskeletal pain with onset of relief within 1 hour and duration up to 12 hours. 6

Additional Conservative Measures

  • Callus debridement by a foot care specialist if present. 2
  • Padding and strapping of the foot. 2
  • Activity modification to reduce excessive loading. 2
  • Physical therapy and stretching exercises. 1

When Conservative Treatment Fails

If no improvement occurs after 6 months of conservative treatment, consider surgical options. 1

Surgical Interventions

For sesamoiditis or first metatarsophalangeal joint pathology:

  • Metatarsal head resection in combination with an offloading device when non-surgical interventions fail. 2
  • Metatarsal-phalangeal joint arthroplasty for hallux ulcers with limited range of motion of the first metatarsophalangeal joint, which may increase healing by 7% and decrease amputations by 52%. 2

For general metatarsalgia:

  • Distal metatarsal osteotomy (Weil osteotomy) is the best-evaluated procedure to decrease prominence of the symptomatic metatarsal head. 7
  • Proximal metatarsal osteotomies are more powerful but technically demanding, used when shortening or elevation is needed. 8
  • Fixation improves union rates and symptom relief compared to non-fixated osteotomies. 8

Critical Clinical Pearls

  • Weight-bearing radiographs are essential, as non-weight-bearing films may underestimate joint instability and malalignment. 1
  • Distinguish sesamoiditis from Morton's neuroma, intermetatarsal bursitis, and plantar plate injuries, as these require different management approaches. 3, 4
  • CT can help differentiate sesamoiditis from stress fractures and bipartite sesamoids when MRI findings are equivocal. 3
  • Avoid local corticosteroid injections in Achilles tendon-related pathology due to rupture risk, though they may be considered for other conditions. 2
  • Metatarsal osteotomy without addressing all pain-producing deformities leads to long-term failure. 9

References

Guideline

Diagnosis and Treatment of Left Foot Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Sesamoiditis Diagnosis and Imaging

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Imaging for Morton's Neuroma

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Dynamic impression insole in rheumatoid foot with metatarsal pain.

Clinical biomechanics (Bristol, Avon), 2012

Research

Metatarsalgia: distal metatarsal osteotomies.

Foot and ankle clinics, 2011

Research

Metatarsalgia: proximal metatarsal osteotomies.

Foot and ankle clinics, 2011

Research

Metatarsalgia.

The Journal of the American Academy of Orthopaedic Surgeons, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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