What does the Mercedes Benz sign on ultrasound indicate in terms of gallbladder (gall bladder) disease?

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Mercedes Benz Sign on Ultrasound

The Mercedes Benz sign indicates gas within fissures or clefts of gallstones, representing a specific radiographic finding of cholelithiasis that is characteristic and diagnostic for the presence of calculi. 1, 2

What the Sign Represents

  • The Mercedes Benz sign appears as gas trapped within the internal fissures of gallstones, creating a three-pronged appearance resembling the Mercedes Benz logo 1, 2

  • This finding is most commonly seen on CT imaging rather than ultrasound, though it can occasionally be identified sonographically 1

  • The gas is believed to be released from solution due to negative pressure within cholesterol stones undergoing internal fissuring related to their crystalline structure 2

Clinical Context and Associations

  • Most reported cases with this sign have been associated with biliary colic or cholecystitis 2

  • When present, this finding is characteristic and definitively indicates the presence of one or more gallstones 2

  • This is a relatively uncommon finding, but when identified, it provides high specificity for cholelithiasis 2

Ultrasound Detection Considerations

  • On ultrasound, gallstones are typically identified as echogenic structures with distal posterior acoustic shadowing that are mobile with patient positioning 3

  • Optimization of gain, frequency, and focal zone settings may be necessary to identify the Mercedes Benz sign or differentiate it from adjacent bowel gas 3

  • The sign may produce comet-tail artifact due to gas, which can be confused with cholesterol stones or pneumobilia 3

Important Differential Considerations

  • Pneumobilia can also produce increased echogenicity and comet-tailing caused by gas in the biliary tree, which must be distinguished from the Mercedes Benz sign 3

  • Emphysematous cholecystitis produces gas in the gallbladder wall and may create similar artifacts 3

  • The Mercedes Benz sign specifically refers to gas within the stone itself, not in surrounding structures 1, 2

Clinical Pitfall

  • The presence of the Mercedes Benz sign or other findings consistent with cholelithiasis does not rule out other life-threatening causes of epigastric or right upper quadrant pain such as aortic aneurysm or myocardial infarction 3

References

Research

Computed tomographic evaluation of gallbladder disease.

Critical reviews in diagnostic imaging, 1987

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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