From the Research
The treatment for Zika virus infection should focus on using nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and acetaminophen, which have been shown to inhibit the replication of Zika virus by inducing the degradation of AXL, a key entry cofactor for the virus 1. The use of NSAIDs for treating Zika virus infection is supported by a study published in the Journal of Virology, which found that these drugs can potently inhibit the entry of Zika virus into host cells and reduce the expression of AXL, thereby preventing the virus from replicating 1. Some key points to consider when using NSAIDs to treat Zika virus infection include:
- The dosage and duration of treatment with NSAIDs will depend on the severity of the infection and the individual patient's response to treatment
- NSAIDs such as ibuprofen and acetaminophen are considered safe for use in pregnant women, which is an important consideration given the risk of congenital Zika syndrome associated with Zika virus infection during pregnancy 1
- Other potential treatments for Zika virus infection, such as antiviral drugs and vaccines, are currently in development but have not yet been approved for clinical use 2, 3, 4, 5 It is essential to note that the treatment of Zika virus infection should prioritize reducing morbidity, mortality, and improving quality of life, and therefore, the use of NSAIDs should be considered as a potential treatment option.