What is the likely diagnosis for a 3-month pregnant patient presenting with vaginal spotting, abdominal cramps, a closed cervix, and a uterus size consistent with gestational age?

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Molar Pregnancy (Gestational Trophoblastic Disease)

The most likely diagnosis is molar pregnancy (option b), given the critical finding of a uterus palpated at the umbilicus in a patient reporting 3 months gestation—this represents size-dates discrepancy that is pathognomonic for molar pregnancy.

Key Diagnostic Features Supporting Molar Pregnancy

Size-Dates Discrepancy

  • A uterus at the umbilical level corresponds to approximately 20 weeks gestational size, yet the patient reports only 3 months (12 weeks) pregnancy 1
  • This marked discrepancy between reported gestational age and actual uterine size is the hallmark clinical finding of complete molar pregnancy 1
  • The excessive uterine enlargement results from proliferating trophoblastic tissue and accumulated fluid 1

Clinical Presentation Consistent with Molar Pregnancy

  • Vaginal spotting with minimal blood-stained discharge is a common presenting symptom of molar pregnancy 2
  • Abdominal cramping can occur as the uterus expands rapidly 3
  • Closed cervix indicates the pregnancy has not yet progressed to expulsion 3, 4
  • Stable vital signs (BP 110/80, HR 88, afebrile) are typical in early molar pregnancy before complications develop 2

Why Other Options Are Less Likely

Incomplete Abortion (Option d) - Excluded

  • Incomplete abortion typically presents with an open cervix with products of conception visible or protruding through the cervical os 4
  • The uterus size would be smaller than expected for gestational age, not larger 3
  • This patient has a closed cervix and enlarged uterus, making incomplete abortion incompatible 4

Ectopic Pregnancy (Option e) - Excluded

  • Ectopic pregnancy presents with a uterus that is smaller than expected for dates, not larger 5, 6
  • The most common finding is a complex adnexal mass (75% of cases), not an enlarged uterus 5
  • At 3 months gestation, an unruptured ectopic would have already caused significant symptoms and likely rupture 6

Breech Pregnancy (Option c) - Not Applicable

  • Fetal presentation cannot be determined at 12 weeks gestation and is irrelevant to the clinical scenario 7
  • Breech presentation does not cause size-dates discrepancy or vaginal bleeding 7

Hydrops Pregnancy (Option a) - Less Likely

  • While hydrops can cause uterine enlargement, it typically occurs later in pregnancy (second/third trimester) 7
  • Hydrops would not explain the degree of size-dates discrepancy seen here 1

Critical Next Steps

Immediate Diagnostic Evaluation Required

  • Ultrasound examination is mandatory to confirm molar pregnancy and visualize the characteristic "snowstorm" or "bunch of grapes" appearance 2
  • Transvaginal ultrasound provides superior resolution for first trimester evaluation 8, 2
  • Quantitative beta-hCG levels should be obtained—molar pregnancy typically shows markedly elevated levels (often >100,000 mIU/mL) 8

Important Clinical Caveat

  • Digital pelvic examination should be avoided until ultrasound excludes placenta previa and vasa previa, though less likely at this gestational age 8, 7
  • The patient requires urgent referral to gynecology or early pregnancy assessment service for definitive diagnosis and management 6
  • Molar pregnancy requires evacuation and long-term beta-hCG monitoring due to risk of persistent gestational trophoblastic disease and malignant transformation 1

References

Guideline

Causes of Second Trimester Spontaneous Abortion

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Sonographic findings in clinically diagnosed threatened abortion.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001

Research

Management of threatened abortion.

Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy, 1996

Research

Cervical vasovagal shock: A rare complication of incomplete abortion case report.

International journal of surgery case reports, 2022

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Vaginal Bleeding at 5 Weeks of Gestation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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