Rosner Index: Cutoff Values and Interpretation
I cannot provide specific cutoff values or interpretation guidelines for the Rosner index because none of the provided evidence sources contain information about the Rosner index or its application in glaucoma assessment.
What the Evidence Does Address
The provided guidelines and research extensively cover:
Risk Assessment Tools Actually Mentioned
- Risk calculators from the Ocular Hypertension Treatment Study (OHTS) are recommended for determining 5-year risk of progression from ocular hypertension to glaucoma, using age, vertical cup-to-disc ratio, pattern standard deviation, central corneal thickness (CCT), and IOP 1
- These calculators are freely available at http://ohts.wustl.edu/risk/calculator.html and as smartphone applications 1
Established IOP-Related Risk Factors
The guidelines identify validated risk factors for glaucoma progression that relate to IOP measurement:
- Central corneal thickness thresholds: CCT ≤510 μm represents higher risk, CCT 511-580 μm intermediate risk, and CCT >580 μm lower risk 1
- Ocular perfusion pressure: Low diastolic perfusion pressure (<50 mmHg) and low systolic perfusion pressure (≤125 mmHg) are associated with higher glaucoma risk 1
- Target IOP reduction: A 20% reduction from baseline mean IOP is recommended as initial target pressure for glaucoma suspects 1
Clinical Implication
If you are seeking a validated tool to assess glaucoma risk based on IOP and other factors, use the OHTS risk calculator rather than searching for alternative indices 1. This tool has been validated in major clinical trials and incorporates the most important risk factors: age, cup-to-disc ratio, pattern standard deviation, CCT, and IOP 1.
Common Pitfall
Clinicians should not rely on IOP correction nomograms or formulas (including any "index") to adjust IOP measurements for corneal thickness, as no standard nomogram correcting applanation IOP measurements for CCT has been validated 1. Instead, diagnose glaucoma using clinical examination of the optic nerve head, imaging, and visual field assessment 1.