Pulmoclear Dosing Information
"Pulmoclear" is not a recognized medication name in standard medical literature, FDA-approved drug databases, or current clinical guidelines. No dosing information exists for a product by this name in the provided evidence or established pharmacological references.
Possible Interpretations
If Referring to Mucolytic/Airway Clearance Therapy
If "Pulmoclear" is a regional or brand name for a mucolytic agent or airway clearance solution, the following evidence-based approaches apply:
For sputum induction and airway clearance:
- Hypertonic saline (2.7% sodium chloride) via high-output ultrasonic nebulizer is the recommended approach, with 20-30 ml loaded into the reservoir at 1 mmol/ml concentration 1
- Normal saline (0.9% sodium chloride) 5 ml every 6 hours may be used to loosen tenacious secretions, though scientific evidence supporting this practice is limited 1
If Referring to Bronchodilator Therapy
For acute bronchospasm or wheezing:
- Nebulized salbutamol (albuterol) 2.5-5 mg every 4-6 hours is the standard dose for moderate to severe symptoms 2
- Metered-dose inhaler with spacer: 2-4 puffs (200-400 μg) every 4-6 hours for mild to moderate symptoms 2
- Continuous nebulization: 0.5 mg/kg per hour up to 10-15 mg/hour for severe, refractory cases 1
For maintenance therapy:
- Two inhalations (180 μg total) every 4-6 hours as needed for adults and children ≥4 years 3
- For exercise-induced bronchospasm prevention: two inhalations 15-30 minutes before exercise 3
Critical Considerations
Device-specific dosing is essential - the nominal dose prescribed varies significantly by delivery device, with lung deposition efficiency ranging from 6-60% depending on the nebulizer or inhaler used 4
Oxygen should be the preferred gas source for nebulization in patients with respiratory distress 1
Monitoring requirements:
- Oxygen saturation should be monitored during nebulized treatments, as unpredictable desaturation may occur 1
- Patients should be reassessed if previously effective doses fail to provide usual response 3
Common Pitfalls
- Inadequate dosing occurs when assuming 2 puffs from an MDI equals a nebulizer treatment - acute settings may require 6-10 puffs 2
- Device must be properly cleaned and dried - medication buildup can block delivery and render the inhaler ineffective 3
- First sputum sample during induction is frequently unrepresentative and should be discarded 1
Recommendation: Clarify the exact generic name and intended indication of "Pulmoclear" with the prescribing source or pharmacy, as this name does not correspond to any standard medication in current medical practice.