Can uterine fibroids increase the risk of infection in the body?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: November 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Uterine Fibroids Do Not Directly Cause Systemic Infections

Uterine fibroids themselves do not cause infections in your body. These are benign smooth muscle tumors of the uterus that do not inherently increase your risk of developing infections 1, 2.

Understanding Fibroids and Infection Risk

Fibroids (leiomyomas) are the most common benign tumors in women of reproductive age, occurring in up to 80% of women by age 50 3. They are non-infectious growths composed of smooth muscle cells and fibroblasts from the uterine wall 4.

When Infection Concerns May Arise

The only scenarios where fibroids relate to infection risk involve medical procedures or devices, not the fibroids themselves:

  • During IUD insertion in women with fibroids: Guidelines note concern about increased infection risk at the time of IUD insertion in women with cervical cancer or endometrial cancer, but this relates to the insertion procedure itself, not fibroids 4

  • Surgical complications: Hysteroscopic myomectomy (fibroid removal) carries a risk of endomyometritis (uterine infection) as a procedural complication, not from the fibroid itself 4

  • Post-hysterectomy: Abscess formation is listed as a potential complication of hysterectomy surgery for fibroids, again related to the surgery rather than the fibroids 4

What Fibroids Actually Cause

Instead of infections, fibroids cause symptoms through mechanical and hormonal mechanisms 1, 2:

  • Heavy menstrual bleeding (potentially leading to anemia) 5
  • Pelvic pressure and pain 1
  • Bowel and bladder dysfunction 1
  • Reproductive issues including infertility 6
  • Sexual dysfunction 6

Important Caveat

If you have fibroids and develop fever, pelvic pain, or unusual discharge, these symptoms suggest a separate infection (such as pelvic inflammatory disease or a sexually transmitted infection) that requires evaluation and treatment, but is not caused by the fibroids themselves 4.

References

Research

Uterine Fibroids: Diagnosis and Treatment.

American family physician, 2017

Research

Uterine fibroids: current perspectives.

International journal of women's health, 2014

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Uterine Fibroids (Leiomyomata) and Heavy Menstrual Bleeding.

Frontiers in reproductive health, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.