What are the typical locations for the 5 points in biostimulation (Bio-Stimulation) therapy?

Biostimulation Point Locations

The term "5 point biostimulation" does not refer to a standardized protocol with universally defined anatomical locations, as biostimulation encompasses diverse therapeutic approaches including laser therapy, injectable treatments, and acupuncture-based techniques that vary by clinical indication and practitioner preference.

Understanding Biostimulation Context

Biostimulation is not a single standardized technique with fixed point locations. The evidence reveals multiple distinct therapeutic modalities using this term:

Laser Biostimulation

• Laser biostimulation involves applying low-energy laser irradiation to wound sites or affected tissues to accelerate healing through mechanisms including enhanced ATP synthesis, increased collagen production, and modulation of inflammatory mediators 1, 2, 3
• Point locations are determined by the anatomical site requiring treatment (e.g., wound margins, surgical sites, or areas of tissue injury), not by predetermined standardized points 2

Injectable Biostimulation (Dermatologic)

• Injectable biostimulation uses intradermal injections of substances like polydeoxyribonucleotides, glucosamine sulfate, N-acetylcysteine, and amino acids to stimulate dermal fibroblast activity 4, 5
• Multiple intradermal injections (0.05-0.1 ml each) are distributed across the treatment area rather than at specific named anatomical points 5
• The injection pattern covers the dermis of the affected skin region with spacing determined by tissue coverage needs, not fixed anatomical landmarks 4

Acupuncture-Based Approaches

If your question refers to acupuncture point selection (which sometimes uses "biostimulation" terminology), the evidence provides condition-specific examples:

For knee pain treatment, a commonly cited 5-point local protocol includes: 6

• GB 34 (Yanglinquan) - Gall bladder meridian point 34
• SP 9 (Yinlinquan) - Spleen meridian point 9
• ST 36 (Zusanli) - Stomach meridian point 36, located on the legs 3 cun below the knee
• ST 35 (Dubi) - Stomach meridian point 35
• Extra point Xiyan - Non-standardized extra point near the knee

For irritable bowel syndrome, frequently used points include: 6

• ST 25 (Tianshu) - Over the middle of the stomach
• ST 36 (Zusanli) - On the legs, 3 cun below the knee
• ST 37 (Shangjuxu) - On the legs, 3 cun below ST 36
• SP 6 (Sanyinjiao) - Inner side of the calf, 3 cun above the medial malleolus
• LR 3 (Taichong) - Dorsum of the foot at the junction of the 1st and 2nd metatarsal bones

Critical Clinical Considerations

• Point selection must be based on the specific therapeutic modality and clinical indication - there is no universal "5 point biostimulation" protocol across all applications 6
• For acupuncture protocols, standardized nomenclature (e.g., GB21, ST36) should be used when available, with anatomical descriptions for non-standard points 6
• Depth of insertion for needle-based techniques should be specified in millimeters, cun measurements, or anatomical tissue levels (subcutaneous, fascia, muscle, periosteum) 6
• The anatomical foot reference in the evidence 7 is unrelated to biostimulation point location and should be disregarded for this question

To provide accurate guidance, clarification is needed regarding: which specific biostimulation modality (laser, injectable, acupuncture) and which clinical condition is being addressed, as point locations are entirely context-dependent 6, 2, 4.