What is the recommended treatment for a pilonidal cyst?

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Treatment of Pilonidal Cyst

Incision and drainage is the primary treatment for an inflamed pilonidal cyst, with antibiotics reserved only for patients showing systemic signs of infection. 1, 2

Acute Pilonidal Abscess Management

Immediate incision and drainage should be performed for any inflamed pilonidal cyst presenting as an abscess, as this is the definitive treatment for all cutaneous abscesses including pilonidal disease. 3, 1 The procedure involves thorough evacuation of pus and probing of the cavity to break up any loculations. 2

When to Add Antibiotics

Antibiotics are generally unnecessary after incision and drainage unless specific criteria are met. 2 Add antibiotics directed against S. aureus only if the patient exhibits systemic inflammatory response syndrome (SIRS), defined as: 1

  • Temperature >38°C or <36°C
  • Tachypnea >24 breaths/minute
  • Tachycardia >90 beats/minute
  • White blood cell count >12,000 or <4,000 cells/µL

An antibiotic active against MRSA is specifically recommended for patients with markedly impaired host defenses or those meeting SIRS criteria. 3, 1

Wound Management After Drainage

After surgical drainage, simply covering the surgical site with a dry dressing is the easiest and most effective treatment. 3 The wound can heal by secondary intention (open healing) or be closed primarily with sutures. 2 One study found that packing the wound caused more pain without improving healing compared to just covering with sterile gauze. 3

Chronic and Recurrent Disease

A recurrent abscess at a previous site mandates evaluation for an underlying pilonidal cyst, as this represents a local predisposing factor that requires definitive surgical management for cure. 3, 1, 2 The presence of recurrent disease indicates the need for more definitive excisional surgery rather than simple drainage alone.

Surgical Options for Definitive Treatment

Multiple surgical approaches exist for chronic pilonidal disease, with varying healing times and recurrence rates: 4

  • Excision with primary closure: Fastest complete healing but 14% wound infection rate and 11% recurrence
  • Marsupialization: Lowest recurrence rate at 4%
  • Wide excision with open healing: Should be reserved only for grossly infected and complex cysts, as healing is prolonged 4

Recurrence Prevention

For patients with recurrent pilonidal abscesses, implement a 5-day decolonization regimen including: 1

  • Twice-daily intranasal mupirocin
  • Daily chlorhexidine washes
  • Daily decontamination of personal items (towels, sheets, clothes)

Common Pitfalls to Avoid

Do not perform Gram stain and culture routinely for uncomplicated pilonidal cysts, as this is not recommended for inflamed epidermoid cysts. 3 However, culture should be obtained if there is extensive surrounding cellulitis or the patient requires systemic antibiotics. 2

Avoid ultrasonographically guided needle aspiration, as this was successful in only 25% of cases overall in randomized trials and is not recommended. 3

References

Guideline

Treatment of Pilonidal Cyst

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Pilonidal Cysts

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Treatment of chronic pilonidal disease.

Diseases of the colon and rectum, 1996

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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