From the Guidelines
You should stop taking Ozempic and Mounjaro immediately if you're pregnant or planning to become pregnant, as these medications are contraindicated in pregnancy due to potential risks to fetal development. According to the 2020 expert consensus decision pathway on novel therapies for cardiovascular risk reduction in patients with type 2 diabetes 1, GLP-1 receptor agonists like semaglutide (Ozempic) have contraindications that include pregnancy or breastfeeding. This is because animal studies have suggested potential risks, and there is limited human data available on the safety of these medications during pregnancy.
When considering the management of type 2 diabetes during pregnancy, it's crucial to prioritize the safety of both the mother and the fetus. Given the potential risks associated with GLP-1 receptor agonists, alternative treatments that have a more established safety profile during pregnancy should be considered. Insulin is often recommended for managing diabetes during pregnancy due to its long history of safe use and effectiveness in controlling blood glucose levels.
Key points to consider:
- Ozempic and Mounjaro are not approved for use during pregnancy.
- These medications should be discontinued if pregnancy is planned or discovered.
- Alternative diabetes management options, such as insulin, are available and recommended during pregnancy.
- The decision to stop Ozempic or Mounjaro and transition to a different medication should be made in consultation with a healthcare provider to ensure the best possible outcomes for both mother and fetus.
From the FDA Drug Label
It is not known if OZEMPIC will harm your unborn baby. You should stop using OZEMPIC 2 months before you plan to become pregnant Talk to your healthcare provider about the best way to control your blood sugar if you plan to become pregnant or while you are pregnant.
Stopping Ozempic and Mounjaro during pregnancy:
- The FDA drug label for Ozempic recommends stopping the medication 2 months before planned pregnancy.
- For patients who are already pregnant, the label advises discussing the best way to control blood sugar with a healthcare provider.
- Since Mounjaro (tirzepatide) is not mentioned in the provided label, but Ozempic (semaglutide) is, and considering the general caution with medications during pregnancy, it is reasonable to consult a healthcare provider for guidance on Mounjaro as well.
- Key points to consider:
- Pregnancy planning: Stop Ozempic 2 months before planned pregnancy.
- Already pregnant: Discuss blood sugar control with a healthcare provider.
- Mounjaro: Consult a healthcare provider for specific guidance 2.
From the Research
Stopping Ozempic and Mounjaro During Pregnancy
- There is limited information available in the provided studies regarding the use of Ozempic (semaglutide) and Mounjaro (tirzepatide) during pregnancy.
- The studies primarily focus on the efficacy and safety of these medications in patients with type 2 diabetes, without specific mention of pregnancy 3, 4, 5, 6, 7.
- However, it is generally recommended to consult a healthcare provider for guidance on medication use during pregnancy, as they can assess individual risks and benefits.
- In the absence of direct evidence, it is essential to follow the advice of a healthcare professional regarding the use of Ozempic and Mounjaro during pregnancy.
Potential Risks and Considerations
- The provided studies do not address the potential risks or benefits of using Ozempic and Mounjaro during pregnancy, making it challenging to provide informed guidance 3, 4, 5, 6, 7.
- Healthcare providers may consider alternative treatments or adjust medication regimens based on individual patient needs and pregnancy status.
- Patients should discuss their medication use and any concerns with their healthcare provider to ensure the best possible outcomes during pregnancy.
Importance of Healthcare Provider Guidance
- Given the lack of specific information on Ozempic and Mounjaro use during pregnancy, it is crucial to consult a healthcare provider for personalized advice 3, 4, 5, 6, 7.
- Healthcare providers can assess individual patient needs, weigh potential risks and benefits, and provide guidance on medication use during pregnancy.