What is monolaurin (monoglyceride of lauric acid)?

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Last updated: April 3, 2025View editorial policy

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From the Research

Monolaurin should be considered as a potential adjunctive treatment for bacterial infections, particularly those caused by Staphylococcus aureus, due to its synergistic effects with β-lactam antibiotics, as evidenced by the most recent study in 2024 1. When using monolaurin supplements, it is essential to start with a lower dose and gradually increase to avoid potential die-off reactions (Herxheimer reactions) that can occur as pathogens are killed.

  • The effectiveness of monolaurin varies depending on the specific condition being treated, with some research suggesting benefits for viral infections, bacterial infections, and candida overgrowth.
  • Monolaurin is available as a dietary supplement typically in capsule form, with common dosages ranging from 500-1000mg taken 1-3 times daily with food.
  • While generally considered safe for most people, monolaurin may cause digestive upset in some individuals.
  • However, monolaurin should not replace prescribed medical treatments, and you should consult with a healthcare provider before starting supplementation, especially if you have existing health conditions or are taking medications. The in vitro study from 2024 1 demonstrated that monolaurin has synergistic effects with β-lactam antibiotics against Staphylococcus aureus, making it a potential candidate for combination therapies.
  • Another study from 2019 2 reviewed the clinical use of monolaurin as a dietary supplement and found that there is limited peer-reviewed evidence for its clinical use, except for topical applications.
  • Additionally, a study from 2018 3 showed that monolaurin has antifungal activity against Candida albicans biofilms in vivo.
  • Other studies, such as those from 2007 4 and 2005 5, have also demonstrated the antimicrobial properties of monolaurin against various pathogens.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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