What is the management of iatrogenic pneumothorax?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 1, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of Iatrogenic Pneumothorax

For stable iatrogenic pneumothorax, simple aspiration using a small-bore catheter (≤14F) should be first-line treatment, achieving success in up to 89% of cases, with chest tube drainage reserved for patients with COPD, those on positive pressure ventilation, or when aspiration fails. 1

Initial Assessment

Assess clinical stability by evaluating:

  • Respiratory rate, heart rate, blood pressure, and room air oxygen saturation 1
  • Ability to speak in complete sentences 1
  • Pre-procedure oxygen saturation (saturation <95% predicts 21% risk of life-threatening events versus 1% if >95%) 2
  • Underlying lung disease, particularly COPD or emphysema 3, 1
  • Whether patient is on mechanical ventilation 1

Treatment Algorithm by Clinical Scenario

Stable Patients NOT on Mechanical Ventilation

Simple aspiration is the first-line intervention:

  • Use an 8F teflon catheter or 16-gauge cannula (at least 3 cm long) 3, 1
  • Insert in the second intercostal space, mid-clavicular line (axillary approach is alternative) 3
  • Infiltrate local anesthetic down to pleura before insertion 3
  • Connect catheter to 50 mL syringe via three-way tap to void aspirated air 3
  • Discontinue if resistance felt, excessive coughing, or >2.5 L aspirated 3
  • Obtain repeat chest radiograph after aspiration 3
  • Success rate reaches 89% without requiring tube drainage 1

Patients with COPD or Underlying Lung Disease

These patients require chest tube drainage more frequently:

  • Place 16F-22F chest tube connected to water seal device 1
  • Apply suction if lung fails to re-expand with water seal alone 1
  • Observe overnight regardless of whether aspiration was performed 3
  • Drainage procedures are less successful in cystic, fibrotic, bullous, or emphysematous lung disease 3

Patients on Positive Pressure Ventilation

Immediate chest tube drainage is mandatory—observation alone is contraindicated:

  • Use 24F-28F large-bore chest tube for anticipated bronchopleural fistula or large air leak 1
  • Positive pressure maintains the air leak, making tube thoracostomy essential 4
  • Never use observation alone in mechanically ventilated patients 1

Tension Pneumothorax (Rare but Critical)

Immediate needle decompression followed by chest tube:

  • Insert cannula of adequate length (minimum 4.5 cm, preferably 7 cm) into second intercostal space, mid-clavicular line 4
  • Standard needles fail in 57% of patients due to chest wall thickness exceeding 3 cm 4
  • Leave decompression cannula in place until chest tube is functioning with confirmed bubbling in underwater seal 4
  • Do not delay treatment for radiographic confirmation—this is a clinical diagnosis 4

Ongoing Management and Monitoring

Serial assessment is essential:

  • Perform serial chest radiographs to assess pneumothorax resolution and lung re-expansion 1
  • Monitor respiratory rate, heart rate, blood pressure, and oxygen saturation continuously 1
  • Check for persistent air leak or early response to treatment 2
  • If lung has not expanded on first radiograph after chest tube insertion, risk of life-threatening events is 25% versus 4% if fully expanded 2

For chest tube management:

  • Wait 24 hours after bubbling stops before removal 3
  • Prescribe adequate oral and intramuscular analgesia 3
  • Remove tube while patient holds breath in full inspiration 3
  • Average drainage duration is 3 days (range 1-15 days) 5

Critical Pitfalls to Avoid

  • Never observe mechanically ventilated patients without chest drainage 1
  • Do not remove chest tube prematurely—confirm complete pneumothorax resolution and cessation of air leak first 1
  • Do not use needles <4.5 cm for tension pneumothorax—failure rates decrease by 7.76% per cm of additional length 4
  • Do not discharge patients with underlying lung disease without overnight observation 3
  • Avoid inadvertent cannula withdrawal or kinking during aspiration—if suspected, reattempt aspiration 3

Post-Discharge Instructions

  • Arrange chest clinic appointment in 7-10 days 3
  • Provide discharge letter instructing patient to return immediately if noticeable deterioration 3
  • Advise avoiding air travel until radiographic changes resolve 3

References

Guideline

Management of Iatrogenic Pneumothorax

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Complications during chest tube drainage for iatrogenic pneumothorax.

European clinical respiratory journal, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Tension Pneumothorax Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Iatrogenic pneumothorax: experience of a Moroccan Emergency Center.

Revista portuguesa de pneumologia, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.