Symptoms of Giardiasis
Giardiasis primarily presents with watery, non-bloody diarrhea, abdominal cramps, bloating, excessive flatulence, and weight loss, typically lasting 2-6 weeks but potentially becoming chronic. 1, 2
Primary Gastrointestinal Symptoms
- Diarrhea is the hallmark symptom—characteristically watery, foul-smelling, and may be greasy or contain mucus, but notably without blood 1, 2, 3
- Abdominal cramps and pain occur frequently, described as cramping discomfort throughout the abdomen 1, 2, 3
- Bloating and excessive gas (flatulence) are prominent features that distinguish giardiasis from other diarrheal illnesses 1, 2, 3
- Belching is commonly reported alongside the flatulence 4
Systemic and Nutritional Symptoms
- Weight loss develops due to malabsorption of nutrients, particularly in prolonged infections 1, 2, 5
- Fatigue and general malaise are commonly reported and can be debilitating 2
- Nausea and vomiting may occur, though less consistently than the diarrheal symptoms 2, 5
- Steatorrhea (fatty stools) can develop from fat malabsorption 5
Disease Course and Duration
- Symptoms typically last 2-6 weeks in acute infections 1
- The infection can become chronic and may recur even after treatment 1, 2
- Persistent symptoms beyond 14 days should raise strong suspicion for giardiasis, particularly in travelers 1, 2
- Unlike most enteritides, giardiasis may cause severe weight loss and generalized discomfort when chronic 4
Clinical Mimicry and Diagnostic Pitfalls
- Symptoms closely resemble functional diarrhea (FD) or diarrhea-predominant irritable bowel syndrome (IBS-D), making clinical distinction difficult 1, 2
- Giardiasis may mimic inflammatory bowel disease or celiac disease 2
- Symptoms alone cannot reliably distinguish giardiasis from other causes of diarrhea—laboratory confirmation is essential 1
- Post-infectious IBS can persist even after successful parasite eradication 2, 6
High-Risk Presentations
- Immunocompromised patients (especially those with HIV) experience more severe and prolonged symptoms 1
- Travelers with persistent diarrhea >14 days require specific parasitic evaluation 1, 2
- Asymptomatic carriage is equally common as symptomatic disease 2, 6