Management of Abdominal Distension
The management of abdominal distension depends critically on distinguishing acute life-threatening causes requiring immediate intervention from chronic functional disorders that respond to conservative measures. 1
Immediate Assessment and Red Flag Identification
Obtain a focused history targeting specific red flags: acute onset with severe pain, constipation, vomiting, fever, tachycardia, weight loss, and hemodynamic instability—these indicate mechanical obstruction, bowel ischemia, or perforation requiring emergency intervention. 1, 2
Physical examination findings guide urgency:
- Complete absence of bowel sounds = paralytic ileus 1
- Diminished bowel sounds with distension = mechanical obstruction (sigmoid volvulus) 1
- Peritoneal signs (rigidity, rebound tenderness) = perforation or ischemia 2
- Asymmetric gaseous distention with left iliac fossa emptiness = sigmoid volvulus 1
Diagnostic Algorithm
Order plain abdominal radiographs immediately in all acute presentations to identify "coffee bean sign" (sigmoid volvulus) or free air (perforation). 1
Obtain CT scan with IV contrast urgently when:
- Plain films are non-diagnostic 1
- Bowel ischemia or perforation is suspected 1, 2
- Patient has peritoneal signs or elevated lactate 1
Essential laboratory testing includes:
- Complete blood count, lactate, electrolytes, renal function, CRP, liver function tests 1, 2
- Stool testing for C. difficile toxin to exclude infectious causes 1
- Serial lactate monitoring in suspected ischemia 1
Management Based on Etiology
Acute Life-Threatening Causes (Immediate Action Required)
For sigmoid volvulus, bowel ischemia, or perforation with peritoneal signs:
- NPO status immediately 1
- IV fluid resuscitation 1
- Nasogastric tube for decompression 1
- Broad-spectrum antibiotics (piperacillin/tazobactam 4 g/0.5 g q6h or meropenem 1 g q6h by extended infusion if septic shock) 2
- Emergency surgical consultation 1
- Serial lactate monitoring 1
Critical pitfall: Never assume absence of peritoneal signs means absence of ischemia—lactate levels and serial examinations are essential. 1
Paralytic Ileus (Conservative Management)
For complete absence of bowel sounds without peritoneal signs:
- NGT decompression 1
- Correct electrolyte abnormalities 1
- Minimize or discontinue opioids 1
- Consider prokinetic agents 1
- Peripheral mu-opioid antagonists (methylnaltrexone for opioid-induced cases) 2
Chronic Functional Abdominal Distension
When Rome IV criteria are met and organic disease is excluded, proceed with stepwise management: 2
First-line dietary interventions:
- Trial dietary restriction for 2 weeks to diagnose food intolerances (lactose, fructose, sucrose) 2
- Low FODMAP diet under gastroenterology dietitian supervision 2
- Avoid in malnourished patients 2
If dietary measures fail, consider hydrogen breath testing for carbohydrate malabsorption or small intestinal bacterial overgrowth (SIBO) in refractory cases. 2
For confirmed or suspected SIBO:
- Rifaximin is the most studied antibiotic option (though expensive and off-label) 2
- Alternative antibiotics include amoxicillin, fluoroquinolones, or metronidazole 2
- Careful patient selection required as none are FDA-approved for SIBO 2
If constipation is present:
- Rule out pelvic floor dyssynergia with anorectal manometry 2
- Use medications for constipation (osmotic laxatives, secretagogues like linaclotide) 2
- Biofeedback therapy if pelvic floor disorder identified 2
For visceral hypersensitivity and abdominophrenic dyssynergia:
- Central neuromodulators (tricyclic antidepressants, SNRIs) to reduce visceral hypersensitivity 2
- Diaphragmatic breathing exercises 2
- Brain-gut behavioral therapies (cognitive behavioral therapy, hypnotherapy) 2
- Antispasmodics (dicycloverine, hyoscine butylbromide) 2
Avoid probiotics—they should not be used to treat abdominal bloating and distention. 2
Special Considerations
For inflammatory bowel disease presenting with distension:
- Endoscopy with biopsy for diagnosis 1
- Treatment with aminosalicylates, corticosteroids, immunomodulators, or biologics based on severity 1
In chronic severe dysmotility:
- Avoid high-dose opioids and cyclizine due to risk of narcotic bowel syndrome and psychological dependence 1, 2
- Consider venting gastrostomy (>20 French gauge) if nasogastric drainage provides symptom relief 2
Critical pitfall: Do not attribute chronic symptoms solely to functional disorders without excluding channelopathies, especially with family history of sudden cardiac death. 1