What are the key components to include when writing an order for a Central Venous Catheter (CVC) exchange?

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Last updated: December 2, 2025View editorial policy

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How to Write a CVC Exchange Order

When writing a CVC exchange order, you must explicitly specify whether you want a new insertion site or a guidewire exchange, as the default terminology "CVC exchange" can lead to dangerous misinterpretation—always write "CVC insertion at new site" for infection-related replacements or "CVC exchange over guidewire" only when preserving venous access in patients with limited sites. 1

Critical Decision Point: New Site vs. Guidewire Exchange

Order a NEW SITE insertion when:

  • Suspected or confirmed catheter-related bloodstream infection (CRBSI) is present 1
  • Purulence, erythema, or signs of infection exist at the exit site or tunnel 1
  • Any evidence of catheter site infection is present 1
  • Guidewire exchange is absolutely contraindicated in these scenarios and increases infection risk significantly 2, 1

Consider guidewire exchange ONLY when:

  • Patient has limited central venous access sites and catheter malfunction (not infection) is the indication 1, 3
  • No signs of infection are present at the catheter site or systemically 1
  • Preserving the existing exit site is clinically necessary 3

Important caveat: Replacement at a new site decreases infection risk compared to guidewire exchange (infection rate 1.8% vs. 19.5% in one study), making new site insertion the safer default choice 3.

Essential Order Components

1. Specify the Exact Procedure Type

Write one of these explicit phrases 1:

  • "CVC insertion at new site" or "CVC placement - new location" (NOT "CVC exchange")
  • Add: "Do NOT exchange over guidewire" to prevent misinterpretation 1

OR if guidewire exchange is truly indicated:

  • "CVC exchange over guidewire" 1

2. Specify Catheter Type

  • "Tunneled, cuffed catheter" for long-term use (>6 months) 2, 1
  • "Non-tunneled catheter" for short-term use 2, 1
  • For long-term home parenteral nutrition, specify tunneled CVCs (Hickman, Broviac, or Groshong) or totally implantable ports 2

3. Specify Insertion Site Preference

  • "Right internal jugular vein" or "Right subclavian vein" (right-sided access preferred to reduce thrombosis risk) 2
  • Avoid femoral vein in adults due to high infection and thrombosis risk 2
  • Avoid subclavian site in hemodialysis patients or those with advanced kidney disease to prevent subclavian vein stenosis 2

4. Specify Catheter Characteristics

  • "Single lumen catheter" (preferred to minimize infection risk) 2
  • Specify catheter size (e.g., "7 French" or "9 French") 1
  • "Minimum number of lumens essential for patient management" 2

5. Request Ultrasound Guidance

  • "Ultrasound-guided CVC placement" (reduces cannulation attempts and mechanical complications) 2, 1

6. Specify Tip Position

  • "Tip position at cavoatrial junction" or "Tip at superior vena cava-right atrium junction" 2, 1
  • This positioning minimizes thrombosis risk 2

7. Request Post-Procedure Confirmation

  • "Post-procedure chest X-ray to confirm catheter position and rule out pneumothorax" 1

8. Specify Sterile Technique Requirements

  • "Use maximal sterile barrier precautions" (cap, mask, sterile gown, sterile gloves, full body drape) 2
  • "Prepare skin with 0.5% chlorhexidine preparation with alcohol" 2
  • "Allow antiseptic to dry per manufacturer recommendations before catheter insertion" 2

Special Considerations for Guidewire Exchange

If guidewire exchange is performed 1, 4:

  • Request fibrin sheath disruption by angioplasty if detected on angiogram during exchange (provides longer time to repeat dysfunction) 1
  • Use Trendelenburg position (5-10 degrees) to reduce air embolism risk 4
  • Direct puncture of previous CVC venous lumen for guidewire insertion rather than cutting the CVC first 4
  • Light manual compression of internal jugular vein venotomy site after catheter removal 4

Sample Order Template

For infection or new site needed:

"CVC insertion at new site. Do NOT exchange over guidewire. Right internal jugular vein preferred. Ultrasound-guided placement. Tunneled, cuffed, single-lumen catheter, 9 French. Tip position at cavoatrial junction. Use maximal sterile barrier precautions. Prepare skin with 0.5% chlorhexidine with alcohol. Post-procedure chest X-ray for position confirmation."

For guidewire exchange (no infection, limited access):

"CVC exchange over guidewire. Right internal jugular vein. Ultrasound-guided. Tunneled, cuffed, single-lumen catheter, 9 French. If fibrin sheath detected, perform angioplasty disruption before completing exchange. Tip position at cavoatrial junction. Use maximal sterile barrier precautions. Post-procedure chest X-ray."

Critical Pitfalls to Avoid

  • Never order routine CVC exchange without specific clinical indication—this does not reduce infection rates and may increase complications 2, 1
  • Never use vague terminology like "CVC exchange" without specifying new site vs. guidewire method 1
  • Never perform guidewire exchange in presence of infection—this is absolutely contraindicated 1
  • Never forget to specify ultrasound guidance—landmark technique has higher complication rates 2, 1
  • Do not place catheters inserted during medical emergencies without replacing them within 48 hours using proper aseptic technique 2

References

Guideline

Central Venous Catheter Exchange Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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