Maintaining Kidney Health with Normal Kidney Function
With normal kidney function, focus on lifestyle modifications to prevent future kidney disease: maintain blood pressure <120/80 mmHg, restrict sodium to <2 g/day, exercise 150 minutes weekly, achieve healthy body weight (BMI 20-25), and avoid nephrotoxic exposures. 1
Blood Pressure Optimization
- Target systolic blood pressure <120 mmHg using standardized office measurement, even with normal kidney function 2
- For those without albuminuria, maintain blood pressure ≤140/90 mmHg at minimum 2
- Blood pressure control is the single most critical modifiable factor for preventing future kidney disease 2
Dietary Modifications
Sodium restriction is paramount:
- Limit dietary sodium to <2.0 g/day (<90 mmol/day) 2, 1
- Focus on reducing processed and restaurant foods, which account for nearly 80% of sodium intake 2
- Choose lower-sodium alternatives at point of purchase rather than restricting salt in cooking 2
Protein intake:
- Maintain protein at 0.8 g/kg body weight/day 1
- Avoid high protein intake >1.3 g/kg/day, which may increase risk of kidney disease development 1
General dietary pattern:
- Emphasize plant-based foods over animal-based foods 1
- Reduce consumption of ultraprocessed foods 1
- Increase intake of fresh fruits and vegetables 2
Physical Activity
- Engage in moderate-intensity physical activity for at least 150 minutes per week 1
- Aim for 30 minutes of exercise 5 times per week 2
- Avoid sedentary behavior 1
Weight Management
- Achieve and maintain healthy body weight with BMI 20-25 kg/m² 2, 1
- Weight loss is recommended for those with obesity 1
Smoking Cessation
Monitoring and Screening
For those at increased risk (age >60, hypertension, diabetes, cardiovascular disease, or family history of CKD):
- Screen with serum creatinine for estimated GFR and urine albumin-to-creatinine ratio 2, 3
- Repeat screening every 3-6 months if risk factors are present 1
- Early detection allows intervention before irreversible damage occurs 3
Avoiding Nephrotoxic Exposures
- Be aware that even with normal kidney function, you are at risk for acute kidney injury from various insults 2
- Avoid nephrotoxic medications when possible (NSAIDs, certain antibiotics) 2
- Stay well-hydrated during illness, especially with vomiting or diarrhea 2
- Inform healthcare providers about any kidney concerns before procedures involving contrast dye 2
Glycemic Control (if diabetic)
- Target hemoglobin A1c of approximately 7% 2, 1
- Good diabetes control prevents development of diabetic kidney disease 2
Common Pitfalls to Avoid
- Do not assume normal labs mean you can ignore prevention: The relationship between acute kidney injury and chronic kidney disease is bidirectional—even single episodes of AKI can lead to future CKD 4
- Do not delay lifestyle modifications: Primary prevention is most effective before any kidney damage occurs 2
- Do not ignore cardiovascular risk factors: Hypertension and diabetes are the leading causes of kidney disease 2, 3
- Do not consume excessive protein: High protein diets (>1.3 g/kg/day) may increase kidney disease risk over time 1