What is the frequency of alcohol-related illnesses, specifically alcohol use disorders (AUD)?

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From the Guidelines

Alcohol-related illnesses occur frequently, with approximately 3.3 million deaths every year, corresponding to nearly 6% of all deaths globally, as reported in the most recent study 1.

Key Statistics

  • Approximately 21% of adults report engaging in risky or hazardous drinking, and the prevalence of current alcohol dependence is about 4% 1.
  • Alcohol misuse contributes to a wide range of health conditions, such as hypertension, gastritis, liver disease and cirrhosis, pancreatitis, certain types of cancer, cognitive impairment, anxiety, and depression 1.
  • The frequency of these illnesses correlates directly with consumption patterns - the more alcohol consumed regularly, the higher the risk.

Screening and Intervention

  • Screening for harmful alcohol consumption should be done systematically in patients, by their general practitioner (GP), and in patients admitted to emergency facilities 1.
  • Screening for ALD should be undertaken in patients with clinical signs suggestive of harmful alcohol consumption or liver cirrhosis 1.
  • Public health policies to reduce population risk for ALD, such as pricing-based policies and regulation of availability, are effective and cost-effective in reducing ALD-related liver deaths 1.

Recommendations

  • Excess alcohol consumption should be addressed using pricing-based policies and regulation of availability 1.
  • Advertising and marketing of alcohol either directly or indirectly should be banned 1.
  • Primary care facilities for managing AUD need to be made widely available 1.
  • Patients identified through screening should undergo brief intervention and referral to a multidisciplinary team 1.

From the Research

Alcohol-Related Illness Frequency

  • Alcohol-related illnesses occur frequently, with alcohol being a leading cause of liver disease worldwide 2.
  • Alcohol use disorders are among the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries, and are associated with high mortality and burden of disease 3.
  • Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all deaths worldwide 4.
  • In the United States, alcohol is the most common substance used, and the spectrum of unhealthy alcohol use is highly prevalent, affecting nearly every organ system 5.
  • Alcohol consumption is a major contributor to the global burden of disease, being a necessary underlying cause for more than 30 conditions and a contributing factor to many more 6.

Prevalence of Alcohol Use Disorders

  • Alcohol use disorders are undertreated, partly due to the high stigma associated with them and insufficient systematic screening in primary health care 3.
  • Despite effective pharmacotherapies, less than 9% of patients who undergo any form of alcohol use disorder treatment receive pharmacotherapies 4.
  • Pharmacologic treatment of alcohol use disorder is underutilized, despite the availability of multiple effective medications 5.

Health Consequences

  • Complications of unhealthy alcohol use affect nearly every organ system, with one of the most frequent and potentially life-threatening being alcohol withdrawal syndrome 5.
  • Alcohol consumption is an important risk factor for many health problems, including infectious diseases, cancer, diabetes, neuropsychiatric diseases, cardiovascular disease, liver and pancreas disease, and unintentional and intentional injury 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Alcohol use disorders.

Lancet (London, England), 2019

Research

The Spectrum of Alcohol Use: Epidemiology, Diagnosis, and Treatment.

The Medical clinics of North America, 2022

Research

The risks associated with alcohol use and alcoholism.

Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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