What is the best imaging modality to evaluate lumpectomy complications in the Emergency Department (ED)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 7, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Best Imaging for Lumpectomy Complications in the Emergency Department

Ultrasound is the recommended initial imaging modality for evaluating lumpectomy complications in the ED, as it provides rapid bedside assessment of common post-surgical complications including seroma, hematoma, abscess, and wound infections without radiation exposure. 1, 2

Primary Imaging Approach

Ultrasound as First-Line Modality

  • Point-of-care ultrasound performed by emergency physicians is the optimal initial test because it can be rapidly performed at bedside, immediately interpreted, and integrated into clinical decision-making without delays associated with formal radiology consultation 1, 2

  • Ultrasound effectively identifies the most common lumpectomy complications:

    • Seroma formation (occurs in 11-65% of cases depending on adjuvant therapy) 3
    • Hematoma (can be visualized with high sensitivity) 4
    • Surgical site infections/abscesses (98% sensitivity, 88% specificity for soft tissue abscess detection) 2
    • Wound complications and fluid collections 1
  • The American College of Emergency Physicians strongly supports emergency ultrasound for diagnostic evaluation of emergency conditions, with soft-tissue/musculoskeletal applications being a core competency 1, 2

Specific Ultrasound Advantages in This Setting

  • No radiation exposure - particularly important in breast cancer patients who may have already received radiation therapy 1
  • Portable and rapid - critical in the ED setting where time-sensitive decisions are needed 1
  • Can guide immediate intervention - allows for bedside aspiration or drainage if indicated 1, 2
  • High negative predictive value (97%) for excluding significant pathology in post-surgical breast patients 1

When to Consider Additional Imaging

Diagnostic Mammography

  • Consider if ultrasound findings are indeterminate or suggest fat necrosis, as mammography can definitively characterize benign post-surgical changes like oil cysts and avoid unnecessary biopsy 1
  • Has limited utility as initial test since it detected no additional cancers beyond ultrasound in post-surgical patients and only visualized 56% of recurrences seen on ultrasound 1

CT Imaging

  • Not routinely indicated for lumpectomy complications unless:

    • Concern for deep infection/necrotizing process extending beyond breast tissue 1
    • Systemic sepsis requiring source identification 1
    • Suspicion of chest wall involvement 1
  • CT has high inappropriate ordering rates (36.3%) in ED abdominal/soft tissue complaints and should be reserved for specific clinical scenarios 5

Common Pitfalls to Avoid

  • Do not delay imaging for formal radiology department ultrasound when emergency physician-performed point-of-care ultrasound is available - this adds unnecessary time without improving diagnostic accuracy 1, 2

  • Do not order mammography as the initial test - it has lower sensitivity than ultrasound for detecting fluid collections and infections in the post-surgical breast 1

  • Recognize that post-lumpectomy complications are common - erythema (6-34%), seroma (11-65%), and infection (6-23%) rates vary based on adjuvant therapy, so clinical correlation is essential 3

  • Be aware that patients with intraoperative radiation therapy (IORT) have significantly higher complication rates (65% seroma rate, 23% infection rate) compared to lumpectomy alone, which may influence imaging interpretation 3

Clinical Integration

The emergency physician should perform focused breast ultrasound looking specifically for:

  • Fluid collections (anechoic or hypoechoic areas suggesting seroma or hematoma)
  • Abscess formation (complex fluid collections with surrounding hyperemia on Doppler)
  • Skin thickening and subcutaneous edema (suggesting cellulitis or infection)
  • Breast tissue architecture disruption beyond expected post-surgical changes 2

If ultrasound demonstrates a drainable collection, bedside aspiration can be performed under ultrasound guidance, providing both diagnostic and therapeutic benefit 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Emergency Ultrasound Applications

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.