What is the cause of dysmenorrhea (painful periods) and metrorrhagia (breakthrough bleeding)?

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Differential Diagnosis for Painful Periods and Breakthrough Bleeding

  • Single Most Likely Diagnosis
    • Dysfunctional Uterine Bleeding (DUB) with associated dysmenorrhea: This condition is characterized by abnormal uterine bleeding that is not associated with any structural or systemic disease. The presence of painful periods (dysmenorrhea) and irregular bleeding patterns, such as breakthrough bleeding, are common manifestations of DUB.
  • Other Likely Diagnoses
    • Endometriosis: A condition where tissue similar to the lining inside the uterus grows outside of it, leading to pain and irregular bleeding.
    • Uterine Fibroids: Benign tumors in the uterus that can cause heavy or irregular menstrual bleeding and painful periods.
    • Adenomyosis: A condition where tissue similar to the lining inside the uterus grows into the muscular walls of the uterus, leading to painful periods and heavy bleeding.
    • Intrauterine Device (IUD) Complications: Certain types of IUDs, especially those that release hormones, can cause changes in menstrual bleeding patterns, including breakthrough bleeding, and may exacerbate or improve dysmenorrhea.
  • Do Not Miss Diagnoses
    • Ectopic Pregnancy: Although less common, an ectopic pregnancy can present with irregular vaginal bleeding and abdominal pain, making it crucial to rule out, especially in women of childbearing age.
    • Malignancies (e.g., Endometrial or Cervical Cancer): While rare, these conditions can cause irregular vaginal bleeding and should be considered, particularly in older women or those with risk factors.
    • Infections (e.g., Pelvic Inflammatory Disease): Can cause pelvic pain and irregular bleeding, and it's essential to diagnose and treat promptly to prevent long-term complications.
  • Rare Diagnoses
    • Von Willebrand Disease: A bleeding disorder that can cause heavy or prolonged menstrual bleeding.
    • Thyroid Disorders: Both hypothyroidism and hyperthyroidism can affect menstrual regularity and may cause changes in bleeding patterns.
    • Pituitary or Adrenal Gland Disorders: Certain conditions affecting these glands can disrupt hormonal balances, leading to irregular menstrual bleeding and other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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