What is the volume in milliliters (mL) of a Lantus (insulin glargine) auto pen injector that contains 100 units of insulin glargine per milliliter (mL)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Lantus Pen Volume

Lantus (insulin glargine) auto pen injectors contain 3 mL of insulin at a concentration of 100 units/mL, providing a total of 300 units of insulin per pen. 1

Pen Specifications

  • Each Lantus SoloStar prefilled pen is a 3 mL single-patient-use device containing 100 units/mL (U-100) insulin glargine 1
  • The total insulin capacity per pen is 300 units, which can be used for multiple injections 1
  • The pen allows dose selection from 1 to 80 units in single-unit increments 1
  • The pen plunger moves with each dose and will only reach the end of the cartridge when all 300 units have been administered 1

Important Clinical Context

  • Lantus is also available as a 10 mL multiple-dose vial containing 100 units/mL 1
  • Standard insulin pens typically contain 300 units (3 mL of U-100 insulin) per cartridge or prefilled pen, which is consistent across most insulin pen products 2
  • The maximum single-dose capacity for most standard insulin pens, including Lantus SoloStar, is 60-80 units per injection 2, 1

Key Safety Considerations

  • Never share insulin pens between patients, even if the needle has been changed, due to risk of serious infection transmission 1
  • Do not use a syringe to remove insulin from the pen, as this can lead to dosing errors 1
  • Each pen should be removed from refrigeration at least 1 hour before injection, as cold insulin is more painful to inject 1

References

Guideline

Maximum Insulin Dose in Pen Devices: Safety and Effectiveness Considerations

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.