What is the best next step for a patient with chronic nasal congestion and decreased sense of smell, with a history of upper respiratory infection and well-controlled mild intermittent asthma (mild intermittent asthma), and normal physical examination and vital signs?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Best Next Step: CT Scan of the Sinuses

The best next step is to obtain a CT scan of the sinuses (option d) to confirm the diagnosis of chronic rhinosinusitis and guide further management, particularly given this patient's comorbid asthma. 1, 2

Rationale for CT Imaging

This patient meets clinical criteria for chronic rhinosinusitis (CRS): symptoms (nasal congestion, decreased sense of smell, intermittent nasal discharge) persisting for 4 months, well beyond the 8-12 week threshold that defines chronic disease. 1, 2 The absence of fever, facial pain, or purulent discharge makes acute bacterial sinusitis unlikely and argues against empiric antibiotics. 1

Why CT is Indicated Now

  • Objective documentation is mandatory for CRS diagnosis. The American Academy of Otolaryngology explicitly states that symptoms alone are insufficient, and objective confirmation through CT imaging or nasal endoscopy is required. 2 Symptoms alone have only 37-73% sensitivity for CRS diagnosis. 2

  • CT is the gold standard for radiologic confirmation of CRS, demonstrating mucosal inflammation, sinus ostial obstruction, and anatomical variants that guide treatment decisions. 1, 2, 3, 4

  • The asthma connection demands thorough evaluation. This patient has comorbid asthma, and 84-100% of patients with asthma have abnormal sinus CT findings. 1 The association between CRS and asthma is bidirectional—treating CRS improves asthma control and reduces exacerbations. 1, 5 Given the potential for CRS to worsen asthma outcomes, prompt diagnosis and treatment is critical. 1, 5

  • Chronic hyperplastic eosinophilic sinusitis is a noninfectious form of CRS often associated with asthma and nasal polyps, which CT can help identify. 1

Why Other Options Are Inappropriate

Observation (Option a)

Observation is not appropriate after 4 months of persistent symptoms. 1, 2 The patient has already had a prolonged period of intermittent symptoms following the initial URI one year ago, with worsening during winter months. Further observation delays diagnosis and risks worsening asthma control. 1

Plain Radiography (Option b)

Plain sinus radiographs are obsolete for CRS evaluation. 3, 4 CT scanning provides superior anatomic detail of the ostiomeatal complex and is essential for surgical planning if medical management fails. 1, 3

Oral Amoxicillin (Option c)

Antibiotics are not indicated here. 1 The patient lacks signs of acute bacterial infection (no fever, no purulent discharge, no facial pain, symptoms >10 days without acute worsening). 1 Acute bacterial rhinosinusitis requires either symptoms ≥10 days from acute onset OR double worsening within 10 days—neither applies to this 4-month chronic presentation. 1 The role of bacterial infection in chronic sinusitis is uncertain, and empiric antibiotics without documented infection risk unnecessary antibiotic exposure. 1

Clinical Pitfalls to Avoid

  • Don't diagnose CRS on symptoms alone. Up to 35% of patients with CRS have normal endoscopic findings, and many conditions mimic CRS symptoms. 2 Objective documentation prevents misdiagnosis and inappropriate treatment.

  • Don't overlook the asthma-rhinosinusitis link. Asthmatics with difficult-to-control disease should be assessed for unsuspected rhinosinusitis with CT or endoscopy, as CRS symptoms may be subtle. 1 This patient's "mild intermittent" asthma may actually be more problematic if underlying CRS is contributing.

  • Don't use plain films. They lack the sensitivity and anatomic detail needed for CRS diagnosis and surgical planning. 3, 4

Next Steps After CT

If CT confirms CRS, initial medical management includes intranasal corticosteroids (most potent for congestion and inflammation), saline irrigation, and consideration of systemic corticosteroids for severe disease. 1, 6 Given the asthma comorbidity, aggressive CRS treatment may improve both sinonasal and pulmonary outcomes. 1, 5 If medical therapy fails, endoscopic sinus surgery should be considered, which has been shown to improve asthma control in this population. 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Criteria for Chronic Rhinosinusitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Imaging of rhinosinusitis and its complications: plain film, CT, and MRI.

Clinical reviews in allergy & immunology, 2006

Research

Chronic Rhinosinusitis with Nasal Polyps and Asthma.

The journal of allergy and clinical immunology. In practice, 2021

Research

Treatment of congestion in upper respiratory diseases.

International journal of general medicine, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.