What is the recommended assessment and workup for a knee injury?

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Knee Injury Assessment and Workup

Plain radiographs (anteroposterior and lateral views) should be obtained as the first-line imaging study for any acute knee injury when Ottawa knee rule criteria are met, including focal tenderness, effusion, or inability to bear weight for 4 steps. 1, 2

Initial Clinical Assessment

History Taking

  • Document the mechanism of injury (twisting, direct blow, hyperextension, motor vehicle accident) 3, 4
  • Identify immediate symptoms: audible pop, immediate swelling (suggesting hemarthrosis), or delayed swelling (suggesting effusion) 4, 5
  • Assess ability to bear weight immediately after injury and currently 1, 2
  • Document mechanical symptoms such as locking, catching, or giving way 2, 6

Physical Examination Priorities

  • Always examine the uninjured knee first for comparison 4
  • Inspect for gross deformity, which mandates immediate radiographs regardless of clinical decision rules 3, 2
  • Palpate for focal tenderness at the patella, fibular head, joint line, and femoral condyles 1, 2
  • Assess for effusion by ballottement or bulge sign 1, 2
  • Test range of motion, specifically ability to flex knee to 90 degrees 2
  • Perform ligament stability testing: valgus/varus stress for collateral ligaments, Lachman test and pivot shift for anterior cruciate ligament, posterior drawer for posterior cruciate ligament 4, 6
  • Evaluate for patellar stability and apprehension 7, 6
  • Perform meniscal testing: McMurray's test, Apley's grind test, and bounce test 4, 6
  • Palpate for tendon gaps suggesting rupture 7

Imaging Algorithm

When to Order Radiographs

Obtain radiographs immediately if ANY of the following are present: 3, 2

  • Age >55 years 2
  • Focal tenderness at patella or fibular head 2
  • Inability to bear weight for 4 steps immediately after injury 2
  • Inability to flex knee to 90 degrees 2
  • Gross deformity 3, 2
  • Palpable mass 3
  • Penetrating injury 3
  • Prosthetic hardware 3
  • Altered mental status (head injury, intoxication, dementia) 3
  • Neuropathy (paraplegia, diabetes) 3
  • History suggesting increased fracture risk 3

Standard Radiographic Views

  • Minimum two views: anteroposterior and lateral (with knee at 25-30 degrees flexion) 2
  • Consider additional views based on clinical suspicion: patellofemoral view, cross-table lateral, internal/external oblique views 2

Advanced Imaging Indications

MRI without IV contrast is the next appropriate study after negative radiographs when: 3, 2

  • Significant joint effusion persists 2
  • Inability to fully bear weight after 5-7 days 2
  • Mechanical symptoms suggesting meniscal injury (locking, catching) 2
  • Joint instability suggesting ligamentous injury 2
  • Suspected occult fracture in adults or skeletally mature children 3
  • Suspected internal derangement (meniscal or ligamentous injury) 3, 2

CT is indicated for: 3, 8

  • Better characterization of fractures identified on radiographs 3, 8
  • Suspected occult fracture when MRI is contraindicated 2

CT angiography or MR angiography is indicated for: 3

  • Knee dislocation with suspected vascular injury (approximately 30% risk with posterior dislocation) 3
  • Abnormal vascular examination (diminished pulses, expanding hematoma) 3

Diagnostic Arthrocentesis

Perform arthrocentesis when effusion is present to: 1

  • Rule out septic arthritis (orthopedic emergency requiring urgent intervention) 1
  • Exclude crystal arthropathy precipitated by trauma 1
  • Identify lipohemarthrosis indicating occult intra-articular fracture despite negative radiographs 1

Synovial Fluid Analysis Priorities

  • Cell count with differential to assess for infection 1
  • Gram stain and culture if infection suspected 1
  • Crystal analysis to exclude gout or pseudogout 1
  • Gross appearance assessment for lipohemarthrosis (fat globules floating on blood) 1

Common Pitfalls to Avoid

  • Do not skip radiographs based solely on ability to bear weight—negative radiographs with weight-bearing ability rule out most fractures requiring surgery, but significant soft tissue injuries may still be present 2
  • Do not rely on clinical examination alone in the first 48 hours—excessive swelling and pain can mask the diagnosis of tendon ruptures and ligamentous injuries 7
  • Consider re-examination after 3-5 days if initial assessment is limited by pain and swelling, particularly for suspected partial tendon tears 7
  • Physician judgment should supersede clinical decision rules when clinical suspicion is high 3, 2
  • Do not routinely order CT, ultrasound, or CT angiography for initial evaluation of knee trauma with normal vital signs and no vascular compromise 1

Specific Injury Patterns

Significant Trauma (Motor Vehicle Accident, Knee Dislocation)

  • Obtain radiographs first 3
  • Assess for vascular injury clinically 3
  • Order CTA if vascular injury suspected (less invasive than conventional angiography with similar accuracy) 3
  • Consider MRI for comprehensive evaluation of soft tissue, osseous, and neural injuries 3

Fall or Twisting Injury with Focal Tenderness/Effusion

  • Obtain radiographs first 3, 1
  • If radiographs negative but clinical suspicion high, proceed to MRI without contrast 3, 2
  • Consider arthrocentesis if significant effusion present 1

Suspected Tendon Rupture

  • Obtain anteroposterior and lateral radiographs 7
  • Perform at least two specific physical examination tests for the suspected tendon 7
  • Re-examine after 3-5 days if initial assessment limited by swelling 7

References

Guideline

Management of Post-Traumatic Knee Effusion

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Imaging Guidelines for Knee Injuries

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Non-operative Management of Acute Knee Injuries.

Current reviews in musculoskeletal medicine, 2024

Research

Physical Examination of the Knee: Meniscus, Cartilage, and Patellofemoral Conditions.

The Journal of the American Academy of Orthopaedic Surgeons, 2017

Guideline

Assessment of Knee Tendon Rupture

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

The painful knee: choosing the right imaging test.

Cleveland Clinic journal of medicine, 2008

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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