What is the diagnosis code for methamphetamine (meth) use disorder?

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Diagnosis Code for Methamphetamine Use

For methamphetamine use disorder, use ICD-10 code F15.10 for mild use disorder, F15.20 for moderate to severe use disorder, or F15.90 for unspecified amphetamine-type substance use.

DSM-5 Diagnostic Framework

The diagnosis of methamphetamine use disorder follows the DSM-5 substance use disorder criteria, which requires meeting at least 2 out of 11 criteria within a 12-month period 1.

Severity Classification

  • Mild disorder (2-3 criteria met): Indicates early problematic use with limited functional impairment 1
  • Moderate disorder (4-5 criteria met): Represents escalating problems with methamphetamine use 1
  • Severe disorder (6 or more criteria met): Reflects significant impairment and loss of control over use 1

Key Diagnostic Criteria to Assess

When evaluating for methamphetamine use disorder, assess for the following 11 criteria 1:

  • Impaired control: Taking larger amounts or for longer than intended; persistent desire or unsuccessful efforts to cut down; significant time spent obtaining, using, or recovering from methamphetamine
  • Social impairment: Failure to fulfill major role obligations; continued use despite social or interpersonal problems; giving up important activities
  • Risky use: Use in physically hazardous situations; continued use despite knowledge of physical or psychological problems
  • Pharmacological criteria: Tolerance (need for increased amounts); withdrawal symptoms; craving (added in DSM-5) 1

Course Specifiers

After establishing the diagnosis, document the clinical course 1:

  • Early remission: ≥3 months but <12 months without meeting criteria (except craving may persist) 1
  • Sustained remission: ≥12 months without meeting criteria (except craving) 1
  • In a controlled environment: When access to methamphetamine is restricted 1
  • On maintenance therapy: If receiving pharmacological treatment (though no FDA-approved medications currently exist for methamphetamine use disorder) 1

Clinical Pitfalls

  • Denial is common: Patients with methamphetamine dependence frequently minimize or deny the severity of their use, particularly regarding continued use despite persistent problems 2. Supplement self-report with collateral information and objective measures when possible 2.

  • High-risk patterns are increasing: From 2015-2019, the prevalence of methamphetamine use disorder or injection use exceeded non-problematic use in 60-67% of users 3. Frequent use (≥200 days/year) occurred in 27.3% of past-year users, and 52.9% met criteria for use disorder 4.

  • Polysubstance use is prevalent: Methamphetamine and cocaine co-use increased 60% from 2015-2019 3. Always assess for other substance use disorders, as polysubstance dependence was eliminated as a separate diagnosis in DSM-5 1.

  • Comorbidities affect diagnosis: Methamphetamine use is associated with psychosis, depression, suicidal ideation, and infectious diseases 4, 3. Substance-induced psychotic symptoms should resolve within 4 weeks of abstinence; persistence beyond this suggests an independent psychotic disorder 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Denial and Diagnosis of Methamphetamine Dependence Severity.

Substance abuse : research and treatment, 2022

Guideline

Duration of Substance-Induced Psychosis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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