What could cause a sudden hemorrhage of a melanocytic nevus (mole) on the inner thigh?

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Differential Diagnosis for a Bleeding Mole on the Inner Thigh

  • Single most likely diagnosis:
    • Trauma: The most common reason for a mole to suddenly bleed is minor trauma, such as scratching, rubbing, or accidental injury, which can cause damage to the skin and lead to bleeding.
  • Other Likely diagnoses:
    • Ingrown hair or folliculitis: If the mole is near a hair follicle, an ingrown hair or folliculitis (inflammation of the hair follicle) could cause irritation and bleeding.
    • Skin infection: A localized skin infection, such as impetigo or cellulitis, could cause redness, swelling, and bleeding around the mole.
    • Mole irritation from clothing or shaving: Friction from tight clothing or shaving can irritate the mole, leading to bleeding.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Melanoma: Although less likely, it's crucial to consider the possibility of melanoma, a type of skin cancer that can cause bleeding from a mole. Any changes in a mole's appearance, including bleeding, should be evaluated by a healthcare professional.
    • Vascular malformation: A vascular malformation, such as a hemangioma, could cause bleeding if it becomes damaged or erodes through the skin.
  • Rare diagnoses:
    • Pyogenic granuloma: A rare, benign skin growth that can bleed easily due to its rich blood supply.
    • Kaposi's sarcoma: A rare type of cancer that can cause skin lesions, including bleeding moles, especially in immunocompromised individuals.
    • Angiosarcoma: A rare, aggressive type of cancer that can cause bleeding skin lesions, although this is extremely uncommon.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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