Unit Conversion: 149 mg/dL Fibrinogen to g/L
149 mg/dL of fibrinogen equals 1.49 g/L.
Conversion Calculation
- To convert mg/dL to g/L, multiply by 0.01 (or divide by 100), since 1 g/L = 100 mg/dL 1, 2
- Therefore: 149 mg/dL × 0.01 = 1.49 g/L
Clinical Context of This Value
This fibrinogen level of 1.49 g/L falls below the critical threshold of 1.5-2.0 g/L recommended for maintaining hemostasis in bleeding patients 3, 4, 5
Normal plasma fibrinogen levels range from 2.0-4.5 g/L (or 200-450 mg/dL), making 149 mg/dL significantly below normal 1, 2
Fibrinogen <150 mg/dL (1.5 g/L) is associated with over fourfold increased 28-day mortality risk in severely injured trauma patients (OR: 4.9,95% CI 1.53 to 15.7) 6
Treatment Implications at This Level
If this patient has significant bleeding, immediate fibrinogen replacement is indicated with either fibrinogen concentrate (3-4 g) or cryoprecipitate (50 mg/kg, approximately 15-20 units in a 70 kg adult) 3, 4, 5
The target fibrinogen level should be maintained above 1.5 g/L for major hemorrhage/trauma, or above 2.0 g/L for obstetric hemorrhage 7, 5
Fibrinogen is the first coagulation factor to fall to critically low levels during major hemorrhage, often dropping below 1.0 g/L before other factors become depleted 3, 1