How to manage hypochondriasis?

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Last updated: December 11, 2025View editorial policy

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Management of Hypochondriasis

Cognitive-behavioral therapy (CBT) is the first-line treatment for hypochondriasis, with demonstrated efficacy in reducing health anxiety and preoccupation with illness, and should be initiated as soon as the diagnosis is established. 1, 2

Initial Assessment and Diagnosis

  • Screen for underlying anxiety disorders, particularly generalized anxiety disorder, as hypochondriasis frequently presents with somatic complaints and health anxiety that may mask an anxiety disorder 3
  • Use the GAD-7 scale (score ≥9 indicates positive screen) to identify generalized anxiety disorder in patients presenting with apparent hypochondriasis 3
  • Recognize that at least half of patients with functional disorders like IBS demonstrate hypochondriacal features, and identifying this pattern helps avoid endless investigation of new symptoms 3
  • Assess for comorbid depression, as hypochondriacal patients have higher rates of mood disorders, and this affects treatment planning 3, 2

Establishing the Therapeutic Relationship

  • The cornerstone of management is establishing a good therapeutic relationship where the physician recognizes that patients have psychological and interpersonal reasons for feeling symptomatic 4, 5
  • Stop trying to cure the patient's symptoms; instead, shift the goal to assisting the patient in coping with symptoms 5
  • Avoid focusing on specific somatic symptoms, as this reinforces the hypochondriacal pattern and leads to inappropriate investigation or treatment 3

Cognitive-Behavioral Therapy (Primary Treatment)

  • Individual CBT is the most effective treatment, with controlled studies demonstrating superiority over behavioral stress management and waitlist controls 1, 2
  • CBT should target four factors that amplify somatic distress: (1) attention paid to symptoms, (2) catastrophic thoughts about symptoms, (3) context in which symptoms are experienced, and (4) mood states 6, 5
  • Group CBT may also be useful as an alternative when individual therapy is not available, though evidence is stronger for individual treatment 2
  • Treatment effects are maintained at 12-month follow-up, indicating durable benefit 1

Pharmacological Treatment

  • Selective serotonin reuptake inhibitors (SSRIs) show promise for hypochondriasis, though evidence is limited by lack of controlled trials 2
  • Consider SSRIs particularly when comorbid depression or anxiety disorders are present 2
  • Pharmacotherapy should not be first-line given the stronger evidence for CBT, but can be used adjunctively or when psychotherapy is unavailable 2, 4

Management of Comorbid Conditions

  • Systematically screen for fibromyalgia, chronic fatigue syndrome, and other functional somatic syndromes, as these overlap substantially with hypochondriacal presentations 3
  • Recognize that patients with multiple somatic complaints report higher levels of health anxiety, neuroticism, and reduced quality of life 3
  • Address underlying mood disorders with appropriate treatment, as antidepressants may improve both depression and hypochondriacal symptoms 3

Avoiding Common Pitfalls

  • Do not order extensive investigations for each new symptom, as this reinforces illness beliefs and increases healthcare utilization 3
  • Avoid referrals to multiple specialists, which fragment care and validate the patient's conviction of serious disease 3
  • Recognize that hypochondriasis and somatization indicate that focusing on specific bowel or other somatic symptoms will not be profitable 3
  • Be aware that supportive or psychoanalytical psychotherapy may help certain patients, but lack of standardized treatments makes them less preferable options 2

Structured Treatment Approach

  • Begin with psychoeducation about the cognitive-behavioral model of health anxiety, explaining how attention, thoughts, and behaviors maintain symptoms 6
  • Use behavioral experiments to test catastrophic health beliefs and reduce checking behaviors 6
  • Teach patients to moderate their attention to bodily sensations through mindfulness and distraction techniques 5
  • Address safety behaviors (e.g., excessive doctor visits, body checking, reassurance seeking) that maintain the disorder 6

References

Research

Two psychological treatments for hypochondriasis. A randomised controlled trial.

The British journal of psychiatry : the journal of mental science, 1998

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Hypochondriasis: treatment options for a diagnostic quagmire.

Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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