Management of Hypochondriasis
Cognitive-behavioral therapy (CBT) is the first-line treatment for hypochondriasis due to its demonstrated efficacy in reducing health anxiety symptoms and should be recommended as the primary intervention.
Understanding Hypochondriasis
Hypochondriasis (also known as health anxiety) is characterized by:
- Preoccupation with fears of having a serious medical illness
- Misinterpretation of benign bodily sensations
- Performance of safety-seeking behaviors (checking, reassurance-seeking)
- Significant distress and functional impairment
The prevalence in primary care settings ranges from 0.8% to 4.5% 1, making it a relatively common condition that clinicians should be prepared to recognize and address.
Diagnostic Considerations
When evaluating a patient with suspected hypochondriasis:
- Look for distressing preoccupation with fears or thoughts of having a serious disease based on physical sensations 2
- Assess for comorbid conditions, as patients with hypochondriasis have higher rates of:
- Anxiety disorders
- Depressive disorders
- Other somatoform disorders 1
- Consider using validated screening tools such as the GAD-2 or GAD-7 scales to assess for underlying anxiety disorders 2
- Rule out medical conditions that could explain physical symptoms
Treatment Approach
First-Line Treatment: Cognitive-Behavioral Therapy
CBT has the strongest evidence base for treating hypochondriasis:
- Meta-analyses show CBT significantly outperforms control conditions with large effect sizes (Hedges's g = 0.95 at post-treatment) 3
- Benefits are maintained at follow-up (Hedges's g = 0.34) 3
- CBT also improves comorbid depression symptoms (Hedges's g = 0.64 at post-treatment) 3
Key elements of effective CBT for hypochondriasis include:
- Cognitive restructuring to address misinterpretations of bodily sensations
- Exposure to health-related triggers with prevention of safety behaviors
- Reduction of body checking and reassurance-seeking behaviors
- Development of more adaptive coping strategies
Important CBT Implementation Factors
Research indicates several factors that influence treatment outcomes:
- Dose-response relationship: A greater number of CBT sessions is associated with larger effect sizes 3
- Pre-treatment severity: Higher pre-treatment severity of health anxiety is associated with greater improvement at follow-up 3
- Comorbid depression: Higher depression symptom severity is associated with lower effect sizes at post-treatment 3
Alternative Psychological Approaches
When CBT is not available or acceptable to patients:
- Behavioral stress management has shown effectiveness, though possibly less specific than CBT 4
- Group CBT may be a cost-effective alternative to individual therapy 1
Pharmacological Treatment
While evidence for medication is more limited than for psychological treatments:
- Selective serotonin reuptake inhibitors (SSRIs) show promise for treating hypochondriasis 1
- Consider pharmacotherapy particularly when:
- CBT is unavailable or inaccessible
- Patient has comorbid depression or anxiety disorders
- Patient has not responded adequately to psychological treatment
Clinical Management Strategies
Recognizing Comorbidities
Systematic questioning to identify comorbid disorders is crucial as:
- Between 20-50% of patients with irritable bowel syndrome (IBS) may have comorbid conditions like fibromyalgia 2
- Up to two-thirds of patients with hypochondriasis may have a comorbid psychiatric disorder 2
- Identifying these comorbidities helps predict severity and guide treatment planning
Avoiding Common Pitfalls
- Excessive medical testing: Repeated negative tests rarely reassure patients with hypochondriasis and may reinforce illness anxiety
- Dismissing physical symptoms: Always perform appropriate medical evaluation before attributing symptoms to hypochondriasis
- Focusing solely on symptom reduction: Treatment should address underlying cognitive processes and behaviors that maintain health anxiety
- Insufficient treatment duration: Longer CBT treatment courses show better outcomes 3
Treatment Algorithm
Initial assessment:
- Confirm diagnosis using diagnostic criteria
- Assess severity and impact on functioning
- Screen for comorbid conditions
First-line treatment:
- Refer for CBT (10-16 sessions recommended)
- Focus on cognitive restructuring and exposure with response prevention
If CBT is unavailable or partially effective:
- Consider SSRI medication
- Alternative psychological approaches (behavioral stress management)
For treatment-resistant cases:
- Combination of CBT and medication
- Longer-term supportive therapy
- Management of comorbid conditions
By following this evidence-based approach, clinicians can effectively help patients with hypochondriasis reduce their health anxiety and improve their quality of life.