What is the cause of left flank pain in a patient with a 5.7 cm left adnexal cystic lesion and no visible kidney stone?

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Left Flank Pain with Normal CT Urogram: Gynecologic Evaluation is Mandatory

The left flank pain in this patient is most likely caused by the 5.7 cm left adnexal cystic lesion, not urolithiasis, and requires immediate pelvic ultrasound for further characterization as recommended in the CT report. 1

Primary Diagnosis: Adnexal Pathology

The CT scan definitively ruled out urolithiasis—no stone, no hydronephrosis, no hydroureter—making renal colic extremely unlikely as the pain etiology. 2 The presence of a 5.7 cm left adnexal cystic lesion is the only significant abnormality identified that could explain left-sided flank pain. 1

Why the Adnexal Mass is the Culprit:

  • Benign adnexal masses are a recognized cause of flank pain in women, particularly when they reach this size (5.7 cm). 1
  • Large ovarian cysts can cause pain through several mechanisms: capsular distension, torsion (partial or complete), rupture, or hemorrhage into the cyst. 3
  • The location (left adnexa) directly correlates with the symptom location (left flank). 1

Immediate Next Steps

Obtain a dedicated pelvic ultrasound within 7 days to characterize the adnexal lesion and assess for complications. 1 This imaging will determine:

  • Whether the mass is ovarian or paraovarian in origin
  • Presence of solid components, septations, or internal blood flow patterns
  • Signs of torsion (absent or decreased Doppler flow)
  • Free fluid suggesting rupture or hemorrhage

Red Flags Requiring Urgent Evaluation:

  • Sudden worsening of pain with nausea/vomiting suggests ovarian torsion—this requires emergent gynecologic consultation within hours, not days. 1
  • Fever or signs of systemic infection could indicate infected cyst or abscess formation. 1
  • Hemodynamic instability may indicate ruptured hemorrhagic cyst. 1

Why This is NOT Urolithiasis

The CT findings make stone disease virtually impossible:

  • Non-contrast CT has 98-100% sensitivity and specificity for detecting urinary stones. 1, 4, 5
  • Absence of hydronephrosis makes stones >5 mm extremely unlikely (ultrasound is 100% sensitive for hydronephrosis). 6
  • Classic renal colic presents as colicky, wave-like pain radiating to the groin/genitals—if the pain pattern differs from this, alternative diagnoses become more likely. 1, 7

Common Pitfalls to Avoid

Do not assume all flank pain is renal in origin—approximately one-third of patients with flank pain have non-urologic causes identified on CT. 1, 4 In women of reproductive age, gynecologic pathology must always be considered. 1

Do not delay gynecologic imaging in young females—some adnexal pathologies (torsion, ectopic pregnancy, hemorrhagic cyst rupture) require urgent intervention. 1

Do not miss ectopic pregnancy—although this patient has an IUD in place (which reduces but does not eliminate ectopic risk), obtain a pregnancy test if there is any menstrual irregularity. 1

Other Incidental Findings Requiring Follow-up

The 2.9 cm hepatic cyst is benign and requires no intervention. 4 The umbilical hernia and L4 Schmorl's node are incidental and unrelated to the acute presentation. 8

References

Guideline

Diagnostic Approach for Flank Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Helical CT scanning: the primary imaging modality for acute flank pain.

The American journal of emergency medicine, 2000

Guideline

Management of Right Flank Pain with History of Kidney Stones

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Approach for Left Flank Pain Radiating to Scapula

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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