What is the recommended assessment and plan for central line placement?

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Assessment and Plan for Central Line Placement

Pre-Procedural Assessment

Use real-time ultrasound guidance for all central line placements to reduce complications and improve success rates. 1, 2

Patient Evaluation

  • Verify indication for central line and document that peripheral access is inadequate or inappropriate 1, 2
  • Assess coagulation status and correct any bleeding disorders or thrombocytopenia before proceeding 3
  • Review patient anatomy for prior central lines, thrombosis history, or anatomic variations 1
  • Identify immunocompromised status (cancer patients, neonates) as this may warrant antibiotic prophylaxis on a case-by-case basis 1

Site Selection Strategy

  • Avoid femoral sites due to increased infection and thrombosis risk, especially in ICU patients 2
  • Prefer internal jugular or subclavian veins for most indications 2
  • Avoid subclavian sites in patients requiring future hemodialysis due to stenosis risk 2
  • Position patient in Trendelenburg (head-down) to increase internal jugular vein filling and cross-sectional area 1, 4
  • Minimize head rotation during internal jugular access to reduce carotid-jugular overlap 1, 4

Pre-Procedure Ultrasound Assessment (Before Sterile Prep)

  • Identify vein anatomy using both short-axis (transverse) and long-axis (longitudinal) views to map vessel relationships 1, 4
  • Check for anatomic variations which occur frequently and can complicate placement 4
  • Confirm vein patency using compression ultrasound to exclude thrombosis 1, 4
  • Use color Doppler imaging to definitively differentiate vein from artery and quantify blood flow 1, 4
  • Note: In hypotensive patients (SBP <60 mmHg), arteries may also be compressible, creating potential confusion 4

Procedural Plan

Maximal Sterile Barrier Precautions (Non-Negotiable)

Apply maximal sterile barriers for every central line insertion to reduce catheter-related bloodstream infections. 1, 2

  • Perform hand hygiene with alcohol-based product or soap and water 2
  • Wear full sterile barriers: hat, mask covering mouth and nose, sterile gown, sterile gloves 1, 2
  • Use large full-body sterile drape covering the patient 1, 2
  • Cover ultrasound probe and cable with sterile cover/shield 1
  • Use sterile ultrasound gel as conductive medium 1

Skin Preparation

  • Apply chlorhexidine-containing solution (minimum 2% CHG) with alcohol for all adults, infants, and children 1, 2
  • For neonates, use chlorhexidine based on clinical judgment and institutional protocol due to potential skin reactions 1
  • If chlorhexidine contraindicated, use povidone-iodine or alcohol 1
  • Allow antiseptic to dry completely before puncturing skin 2

Six-Step Ultrasound-Guided Insertion Technique

Step 1: Real-Time Needle Guidance

  • Position yourself so insertion site, needle, and ultrasound screen are in your line of sight 1, 4
  • Hold ultrasound probe with non-dominant hand while advancing needle with dominant hand 1, 4
  • Use either short-axis/out-of-plane OR long-axis/in-plane view for needle visualization 1, 4
  • Constantly visualize needle tip throughout entire approach to the vein 1, 4

Step 2: Confirm Needle Position

  • Verify needle tip is centrally positioned in the vein before advancing guidewire using real-time ultrasound 1, 4
  • Confirm venous (not arterial) placement using ultrasound, manometry, or pressure waveform analysis 4

Step 3: Confirm Guidewire Position

  • Visualize guidewire in both short-axis and long-axis views after advancement 1, 4
  • If complete guidewire cannot be located in procedural field, order chest X-ray to check for wire retention 4

Step 4: Confirm Catheter Position

  • Visualize catheter in both short-axis and long-axis views after placement over guidewire 1, 4
  • Verify catheter tip position between lower third of superior vena cava and upper third of right atrium using intraoperative fluoroscopy, post-operative chest X-ray, or intracavitary ECG 1, 2

Catheter Selection Considerations

  • Consider antimicrobial-coated catheters (chlorhexidine-silver sulfadiazine or antibiotic-impregnated) as they reduce catheter colonization 1
  • Note: Chlorhexidine-coated catheters carry rare risk of anaphylaxis 1
  • Evidence for reduced bloodstream infection with coated catheters is equivocal 1

Post-Procedural Management

Immediate Post-Procedure

  • Monitor vital signs (temperature, pulse, blood pressure, respiratory rate) every 4 hours after placement 2
  • Apply sterile transparent dressing over insertion site 2
  • If unintended arterial cannulation with large-bore catheter occurs, leave catheter in place and immediately consult vascular surgery or interventional radiology 4

Dressing and Maintenance

  • Replace transparent dressings no more than once weekly unless soiled or loose 2
  • Perform routine flushing with saline after any infusion or blood sampling 2
  • Replace administration sets and needleless connectors at least every 7 days (within 24 hours after blood products or lipid emulsions) 2

Infection Prevention Bundle

  • Consider daily chlorhexidine bathing for ICU patients over 2 months of age to reduce infection risk 2
  • Perform hand hygiene before every catheter manipulation 2, 5
  • Clean injection ports with 70% alcohol before accessing the system 3
  • Evaluate daily for continued need and remove as soon as no longer necessary 5

Critical Pitfalls to Avoid

Sterile technique breaks during placement are associated with 71% of central line-associated bloodstream infections in trauma patients. 6

  • Never compromise on maximal sterile barriers, even in emergency situations—this is the single most important factor in preventing infections 6, 7
  • Changing a "dirty" line within 24 hours does not reduce infection risk—proper initial technique is essential 6
  • Do not routinely administer prophylactic IV antibiotics except for immunocompromised patients or high-risk neonates on a case-by-case basis 1
  • Do not use heparin immediately before or after lipid-containing infusions due to precipitation and emboli risk 3
  • Hand hygiene is the single most crucial nursing intervention to prevent infections 5

Quality Assurance

  • Use standardized equipment sets and checklists for placement and maintenance 1, 2
  • Ensure trained assistant is present during placement 1
  • Empower staff to stop procedures if protocols are not followed 2
  • Track compliance with bundle elements using checklists 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Central Line Placement and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Heparin Dosage for Port Flushes

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Ultrasound-Guided PICC Line Insertion

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Central Line Care and Management: Adopting Evidence-Based Nursing Interventions.

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2021

Research

Central line-associated bloodstream infections: prevention and management.

Infectious disease clinics of North America, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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