What is the pre-trematic nerve of the 2nd (second) pharyngeal arch?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Pre-trematic Nerve of the Second Pharyngeal Arch

The chorda tympani is the pre-trematic nerve of the 2nd pharyngeal arch (answer c). 1

Anatomical Basis

The facial nerve (cranial nerve VII) is the nerve of the second pharyngeal (hyoid) arch and follows the classic branchiomeric pattern with both pre-trematic and post-trematic branches 1:

Pre-trematic Branch

  • The chorda tympani represents the pre-trematic branch, arising just before the facial nerve exits the stylomastoid foramen 1
  • This nerve passes through the middle ear cavity and distributes to structures derived from the mandibular (first) arch, though it originates from the second arch nerve 2
  • The chorda tympani carries taste fibers from the anterior two-thirds of the tongue and preganglionic parasympathetic fibers to the submandibular ganglion 1

Post-trematic Branches

  • The main trunk of the facial nerve after exiting the stylomastoid foramen represents post-trematic distribution 1
  • These branches (temporal, zygomatic, buccal, mandibular, and cervical) supply muscles of facial expression derived from second arch mesoderm 1
  • The nerve to the stylohyoid and posterior digastric muscles are also post-trematic branches 1

Embryological Context

The branchiomeric pattern is highly conserved throughout vertebrate evolution, with each pharyngeal arch having characteristic pre-trematic and post-trematic nerve distributions 3. Studies in chondrichthyes (cartilaginous fish) demonstrate that the homologue of the chorda tympani serves as the pre-trematic branch of the facial nerve, supplying the floor of the mouth 4.

Incorrect Options Explained

  • Option a (nerve to submandibular gland): This is carried by the chorda tympani but is not itself a named nerve branch 1
  • Option b (nerve to nasal mucosa): This is supplied by branches of the maxillary division of the trigeminal nerve, not the facial nerve
  • Option d (nerve to parotid): The parotid receives parasympathetic innervation from the glossopharyngeal nerve (CN IX) via the lesser petrosal nerve 5
  • Option e (nerve to lacrimal duct): Lacrimal gland innervation comes from the greater petrosal nerve (another facial nerve branch) via the pterygopalatine ganglion 1

References

Research

The anatomy of the facial nerve.

Ear, nose, & throat journal, 1990

Research

Development and evolution of the pharyngeal apparatus.

Wiley interdisciplinary reviews. Developmental biology, 2014

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.