What is the approach to taking a history for a patient who has attempted suicide with drugs?

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History Taking for Drug Overdose Suicide Attempts

When evaluating a patient who has attempted suicide with drugs, you must immediately establish rapport while systematically gathering information from both the patient AND a third party—regardless of how mild the attempt appears—as this collateral information is essential and mandatory for safe disposition. 1

Essential Components of the Suicide History

Direct Assessment of Suicidal Intent and Planning

  • Ask directly about suicidal thoughts: Begin with "Have you ever thought about killing yourself or wished you were dead?" followed immediately by "Have you ever done anything on purpose to hurt or kill yourself?" 1
  • Determine current suicidal state: Assess whether the patient is still thinking of suicide, as this represents the highest risk factor for future attempts 1
  • Elicit specific suicide plans: Ask explicitly "If you were to kill yourself, how would you do it?" to determine if a concrete plan exists 1
  • Assess intent at time of attempt: Determine whether the patient truly wanted to die or was seeking help/relief from distress 1
  • Evaluate timing and impulsivity: Most adolescent overdoses are impulsive and occur during disputes with family or romantic partners 1

Details of the Current Attempt

  • Identify the specific substances ingested: Document all medications taken, including over-the-counter analgesics (most common), benzodiazepines (34% of cases), neuroleptics (23%), and paracetamol/acetaminophen (23%) 2
  • Determine quantity and timing: Establish how much was taken and when, as this guides medical management 2
  • Assess lethality of method chosen: Recognize that while ingestion is the most common attempt method in adolescents, firearms remain the most lethal means 1, 3
  • Clarify how substances were obtained: Were they prescribed to the patient, taken from family members, or purchased over-the-counter? 4, 5

Psychiatric History and Mental State Examination

Look systematically for signs of clinical depression 1:

  • Depressed mood most of the time or loss of interest/pleasure in activities
  • Weight changes, sleep disturbances (insomnia or hypersomnia)
  • Psychomotor agitation or retardation, fatigue
  • Feelings of worthlessness, guilt, or hopelessness about the future
  • Difficulty concentrating, indecisiveness
  • Recurring thoughts of death
  • Critical caveat: Adolescents may present with irritability rather than depressed mood as the primary manifestation 1

Screen for mania or hypomania 1:

  • Elated, expansive, or irritable mood with inflated self-esteem
  • Decreased need for sleep, pressured speech, racing thoughts
  • Distractibility, excessive goal-directed activities
  • Impulsive behaviors (hypersexuality, foolish spending, uninhibited remarks)

Assess for psychotic symptoms: Patients who are delusional, hallucinating, or threatening violence to others require psychiatric evaluation before discharge 1

Document substance use: Substance abuse alone or combined with mood disorders dramatically increases risk, and alcohol/drugs have dangerous disinhibiting effects 1

Prior Suicide Attempts and Family History

  • Document all previous suicide attempts: Prior attempts are among the strongest predictors of future attempts and completed suicide 1
  • Obtain family history of suicide: Suicidal behaviors in biological relatives increase risk 6
  • Assess for self-harm behaviors: Ask about cutting, burning, or other non-suicidal self-injury 1

Critical Risk Factors to Identify

Demographics and social factors 1:

  • Male gender (higher lethality), living alone
  • Recent separation, divorce, or interpersonal conflicts 4
  • Gay, lesbian, or bisexual orientation (2-7 fold increased risk for attempts) 1
  • Runaway status or homelessness 1

Abuse and trauma history 1:

  • Physical and sexual abuse must be assessed routinely: 15-20% of female attempters have abuse history, and abuse increases attempt risk even when controlling for other factors
  • Conversely, any patient with known abuse history requires assessment for suicidality

Access to lethal means 1:

  • Explicitly ask about firearms in the home: This is mandatory, as firearms are the most common method for completed adolescent suicide in the United States
  • Document availability of medications, both prescription and over-the-counter
  • Assess whether the patient knows where these items are stored

Mandatory Third-Party Information

You must obtain collateral information from family, friends, or other sources regardless of how mild the attempt appears 1:

  • Verify the patient's account of events and mental state
  • Assess family dynamics and level of supervision available
  • Determine whether responsible adults can "sanitize" the environment by removing firearms and lethal medications
  • Evaluate family's understanding of the seriousness and their commitment to safety planning

Important note on confidentiality: While confidentiality is important in adolescent care, safety takes precedence—explain this to the patient at the outset so they understand information will be shared with parents/guardians 1

Disposition-Critical Assessment

Indicators for Psychiatric Hospitalization

Admit patients who have 1:

  • Persistent wish to die despite intervention
  • Clearly abnormal mental state (psychosis, severe depression, mania)
  • Inadequate supervision or support at home
  • Refusal to agree to safety measures (though contracts alone are insufficient)

Requirements Before Discharge Consideration

Discharge is only appropriate when ALL of the following are met 1:

  • Adequate supervision and support confirmed for the next several days
  • A responsible adult has agreed to remove all firearms and secure/dispose of potentially lethal medications
  • Follow-up appointment scheduled before leaving the emergency department (or telephone contact established with plan for staff to initiate contact if family doesn't follow through)
  • Patient's mental state has stabilized sufficiently

Critical Pitfalls to Avoid

  • Never dismiss suicidal statements as attention-seeking or unimportant: Even seemingly minor attempts require full evaluation 1
  • Never rely on "no-suicide contracts": These have no proven efficacy and create false reassurance; the patient may not be in a mental state to understand the contract 1, 7, 8
  • Never discharge without third-party information: The patient's self-report alone is insufficient for safe disposition 1
  • Never assume over-the-counter medications are "safe": Acetaminophen and other OTC analgesics are commonly used and can be lethal 2, 5
  • Do not overlook substance use: Alcohol and drugs dramatically increase risk through disinhibition 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Characteristics of Presentations to the Emergency Department Following Attempted Suicide with Drugs.

International journal of environmental research and public health, 2021

Research

A Stepwise Approach for Preventing Suicide by Lethal Poisoning.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS, 2021

Research

Suicide attempt by drug overdose.

American family physician, 1986

Guideline

Daridorexant Use in Psychiatric Patients with Suicidal Thoughts

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Situational Depression, Anxiety, and Suicidal Ideation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Bipolar Disorder with Suicidal Ideation and Breakthrough Depression

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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