From the Guidelines
Coarctation of the aorta (CoA) is not directly related to a hypoplastic forearm.
Relationship between CoA and other conditions
- CoA is considered as part of a generalized arteriopathy and can occur as a discrete stenosis or as a long, hypoplastic aortic segment 1.
- It is typically located in the area where the ductus arteriosus inserts, and is associated with other lesions such as bicuspid aortic valve (BAV), intracerebral aneurysms, and ascending aortic aneurysms 1.
- CoA may also be associated with syndromes such as Turner syndrome (TS), with up to 12.6% of females diagnosed with CoA also having TS 1.
Lack of evidence for relationship with hypoplastic forearm
- There is no mention of a hypoplastic forearm in the provided evidence as a associated condition with CoA 1.
- The evidence focuses on the association of CoA with other cardiovascular conditions and syndromes, but does not discuss any relationship with forearm hypoplasia.
From the Research
Relationship Between Coarctation of the Aorta and Hypoplastic Forearm
- There is no direct evidence in the provided studies that discusses the relationship between coarctation of the aorta (CoA) and a hypoplastic forearm.
- However, studies have discussed the relationship between CoA and hypoplasia of the aortic arch, which may be relevant to understanding the potential relationship between CoA and hypoplastic forearm 2, 3, 4, 5, 6.
- Coarctation of the aorta is often associated with hypoplasia of the aortic arch, which can lead to severe cardiovascular complications if left untreated 3, 4.
- Some studies have investigated the growth and development of the hypoplastic aortic arch after repair of CoA, with findings suggesting that the arch can grow and develop normally after repair 6.
- Additionally, research has shown that persistent aortic arch hypoplasia after CoA treatment is associated with late systemic hypertension 5.
Aortic Arch Hypoplasia and Coarctation of the Aorta
- Aortic arch hypoplasia is a common feature in patients with CoA, and its severity can vary 2, 4, 6.
- The management of CoA and aortic arch hypoplasia often involves surgical or transcatheter repair, with the goal of relieving obstruction and promoting normal blood flow 3, 4.
- The choice of treatment depends on various factors, including the severity of the CoA and aortic arch hypoplasia, as well as the presence of other congenital heart defects 4.