What is the cause of Straight Back Syndrome in Mitral Valve Prolapse (MVP)?

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Last updated: April 7, 2025View editorial policy

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From the Research

Straight back syndrome is a known cause of mitral valve prolapse (MVP) due to the altered cardiac positioning and mechanical distortion of the mitral valve apparatus resulting from the congenital absence of normal thoracic spine curvature. This condition is characterized by a compressed chest cavity, which pushes the heart forward and changes the spatial relationship between the mitral valve and its supporting structures. The flattened thoracic spine reduces the anteroposterior diameter of the chest, causing the heart to rotate slightly and creating abnormal tension on the mitral valve apparatus, as discussed in 1.

Key Features of Straight Back Syndrome

  • Congenital absence of normal thoracic spine curvature
  • Compressed chest cavity altering cardiac positioning
  • Mechanical distortion of the mitral valve apparatus
  • Association with mitral valve prolapse and other cardiac conditions

The diagnosis of straight back syndrome is confirmed through chest radiographs showing decreased thoracic kyphosis and echocardiography demonstrating mitral valve prolapse, as noted in 2. Treatment focuses on managing MVP symptoms rather than correcting the spinal abnormality, though severe cases with significant cardiac compression might occasionally warrant surgical intervention, as suggested in 3. It's essential to consider the latest research progress in this disease, as summarized in 1, to provide effective diagnosis and treatment.

Clinical Implications

  • Patients with straight back syndrome may present with a flat thoracic spine on physical examination or imaging
  • Associated conditions may include pectus excavatum (funnel chest)
  • Diagnosis requires chest radiographs and echocardiography
  • Treatment prioritizes managing MVP symptoms, with surgical intervention considered in severe cases, as discussed in 4 and 5.

References

Research

An interesting case of straight back syndrome and review of the literature.

Asian cardiovascular & thoracic annals, 2016

Research

Straight Back Syndrome.

Thoracic surgery clinics, 2017

Research

Mitral valve prolapse.

Disease-a-month : DM, 1987

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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