What are the recommendations for using the push-pull method for blood draws from Central Venous Catheters (CVCs) in pediatric patients?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 17, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Push-Pull Method for Blood Draws from Pediatric Central Venous Catheters

Direct Recommendation

The push-pull method is a safe and reliable waste-free blood sampling technique for pediatric central venous catheters that should be implemented as standard practice in the PICU to reduce iatrogenic blood loss and prevent transfusion-related complications. 1

Evidence Supporting the Push-Pull Method

The push-pull technique has been validated specifically for pediatric CVC blood sampling through evidence-based practice implementation in the PICU setting 1. This method eliminates the traditional discard volume, thereby significantly reducing sampling-related blood loss—a critical concern in pediatric patients who are particularly vulnerable to iatrogenic anemia 1.

Key Implementation Points

The technique involves:

  • Drawing blood into the syringe and immediately pushing it back into the catheter to mix with the dead space volume 1
  • Repeating this push-pull action several times to ensure adequate mixing 1
  • Then drawing the sample for laboratory testing without any discard volume 1

This approach has been demonstrated to provide accurate laboratory results while protecting pediatric patients from cumulative blood loss that can necessitate transfusions 1.

Critical CVC Management Considerations

Dedicated Lumen for Specific Uses

When using CVCs for blood sampling in pediatric patients, one lumen should be dedicated exclusively to parenteral nutrition if PN is being administered 2. However, for routine monitoring in patients on long-term PN, blood sampling via CVC is acceptable when full aseptic protocol is followed 2.

Multi-Lumen Catheter Risks

Multi-lumen catheters carry increased infection risk (10-20% sepsis rate) compared to single-lumen catheters (0-5% sepsis rate) 2. When multi-lumen CVCs are necessary, strict protocols must be maintained: one lumen reserved exclusively for its designated purpose, no blood sampling from PN lumens during active infusion, and avoidance of blood transfusion or central venous pressure measurement through dedicated lumens 2.

Common Pitfalls to Avoid

Do not routinely use the CVC for blood sampling if it compromises line integrity or increases manipulation frequency, as this elevates infection risk 2. The exception is patients requiring long-term PN where routine monitoring necessitates CVC access, provided strict aseptic technique is maintained 2.

Avoid using CVCs with catheter-to-vessel diameter ratios >0.45, as this increases thrombosis risk 3. Right-sided insertion is strongly preferred over left-sided (relative risk of thrombosis 4.4 for left-sided) 3.

Age-Specific Considerations

Pediatric CVC complications are closely linked to age, body size, and immune status 4. Younger children and infants face higher complication rates and require more careful monitoring during blood sampling procedures 4. The bimodal age distribution of central venous thrombosis—with peaks in the neonatal period and adolescence—means heightened vigilance is needed in these populations 3.

Safety Profile

The push-pull protocol has been evaluated and found safe for standard PICU use across different CVC types 1. This waste-free approach directly addresses the major source of blood loss in critically ill children while maintaining laboratory accuracy 1.

References

Research

A Standard Push-Pull Protocol for Waste-Free Sampling in the Pediatric Intensive Care Unit.

Journal of infusion nursing : the official publication of the Infusion Nurses Society, 2018

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Central Venous Thrombosis Risk Factors and Prevention

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Central venous catheter use in the pediatric patient: mechanical and infectious complications.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.