What is the most common clinical presentation of catheter-associated urinary tract infection (UTI)?

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Last updated: December 18, 2025View editorial policy

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Most Common Clinical Presentation of Catheter-Associated UTI

Fever is the most common clinical presentation of catheter-associated urinary tract infection, often accompanied by systemic symptoms rather than localized urinary complaints. 1

Primary Clinical Manifestations

The 2024 European Association of Urology guidelines explicitly list the signs and systemic symptoms compatible with catheter-associated UTI, with fever being the predominant presenting feature, followed by:

  • New onset or worsening of fever 1
  • Rigor (shaking chills) 1
  • Altered mental status 1
  • Malaise or lethargy with no other identified cause 1

Secondary Manifestations

Additional presentations include:

  • Flank pain or costovertebral angle tenderness 1
  • Acute hematuria 1
  • Pelvic discomfort 1
  • Dysuria, urgency, frequency, or suprapubic pain/tenderness (primarily in patients whose catheter has been removed) 1

Why Fever Predominates Over Other Options

Frequency (Option D) is notably absent as a primary symptom in catheterized patients because the catheter bypasses normal voiding mechanisms—patients cannot experience urinary frequency while continuously draining through an indwelling catheter. 1

Spasticity (Option C) is not a recognized clinical manifestation of catheter-associated UTI in the major guidelines, though it may occur in patients with neurogenic bladder from other causes. 1

Malaise (Option B), while present, is a nonspecific systemic symptom that accompanies fever rather than being the primary presenting feature. 1

Clinical Context and Severity

Catheter-associated UTIs represent serious infections with significant morbidity and mortality implications:

  • Approximately 20% of hospital-acquired bacteremias arise from the urinary tract 1
  • Mortality associated with CA-UTI bacteremia is approximately 10% 1
  • The systemic nature of presentation (fever, rigors, altered mental status) reflects the propensity for these infections to progress to bacteremia and sepsis 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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