What is the condition characterized by a purple and hypertrophied tip of the nose, potentially more prevalent in males?

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Differential Diagnosis for Purple and Bulbous Nose Tip

  • Single most likely diagnosis
    • Rhinophyma: This is a subtype of rosacea that is characterized by a bulbous, enlarged, and purple nose tip. It is more common in males and is often associated with other symptoms of rosacea, such as flushing and acne-like lesions.
  • Other Likely diagnoses
    • Rosacea: While not as specific as rhinophyma, rosacea can cause redness, swelling, and a bulbous appearance of the nose, which may be mistaken for a purple discoloration.
    • Lupus pernio: This is a type of cutaneous sarcoidosis that can cause purple lesions on the nose, although it is less common than rhinophyma.
  • Do Not Miss
    • Basal cell carcinoma or squamous cell carcinoma: Although less likely, these skin cancers can cause lesions on the nose that may appear purple or bulbous. Missing a diagnosis of skin cancer could have serious consequences.
    • Granuloma faciale: This is a rare condition that can cause purple lesions on the face, including the nose, and can be mistaken for other conditions.
  • Rare diagnoses
    • Sarcoidosis: While lupus pernio is a form of sarcoidosis, systemic sarcoidosis can also cause skin lesions, including on the nose.
    • Angiosarcoma: This is a rare and aggressive skin cancer that can cause purple lesions on the face, including the nose.
    • Cryoglobulinemia: This is a rare condition that can cause purple lesions on the face and nose due to the formation of cryoglobulins, which are proteins that precipitate in cold temperatures.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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