What is the workup for econophthalmos (exophthalmos) in an adult?

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From the Guidelines

A comprehensive econoperisis workup for an adult is not directly addressed in the provided evidence, which focuses on adult strabismus and neuro-ophthalmic disorders. However, based on the available information, I recommend a thorough medical and ocular history assessment, including specific questions about patient symptoms, speed of onset of the condition, and possible associated neurologic symptoms 1. This should be followed by a comprehensive eye examination with particular attention to sensorimotor exam, evidence of ptosis and anisocoria, and pupillary responses in bright and dim illumination 1. Key elements of the examination should include:

  • A detailed medical and ocular history
  • A comprehensive eye examination
  • Evaluation of sensorimotor function
  • Assessment of ptosis and anisocoria
  • Pupillary responses in bright and dim illumination
  • Fundus examination to evaluate for the presence of papilledema or optic atrophy Given the lack of direct evidence on econoperisis, it is essential to prioritize a thorough medical evaluation to rule out underlying conditions that may be contributing to the patient's symptoms 1. In the context of real-life clinical medicine, a comprehensive and multidisciplinary approach is crucial to ensure the best possible outcomes for the patient.

From the Research

Eosinophilic Pneumonia Workup in Adults

  • The workup for eosinophilic pneumonia in adults involves a combination of clinical evaluation, laboratory tests, and imaging studies 2, 3, 4, 5.
  • A thorough history and physical examination, including travel and medication history, are essential in identifying potential causes of eosinophilic pneumonia 3, 5.
  • Laboratory tests, such as complete blood counts and bronchoalveolar lavage (BAL) fluid analysis, can help diagnose eosinophilic pneumonia and identify the underlying cause 2, 4, 5.
  • Imaging studies, including chest radiographs and computed tomography (CT) scans, can help identify the extent and distribution of lung involvement 6.
  • The diagnosis of eosinophilic pneumonia is often confirmed by the presence of eosinophils in BAL fluid or lung tissue, and the exclusion of other disease processes that can present with similar symptoms 2, 3, 4, 5.

Diagnostic Criteria

  • The diagnostic criteria for eosinophilic pneumonia include:
    • Peripheral blood eosinophilia (typically ≥500 cells/mm3) 2, 4
    • Pulmonary symptoms and physical examination findings consistent with eosinophilic pneumonia 2, 3, 4
    • Radiographic evidence of pulmonary disease, such as bilateral reticular densities or ground-glass opacities 6
    • Histopathologic evidence of tissue eosinophilia in a lung or pleura biopsy specimen and/or increased eosinophils in BAL fluid 2, 4

Treatment

  • The treatment of eosinophilic pneumonia depends on the underlying cause and the severity of the disease 2, 3, 4, 5.
  • Glucocorticoids are the mainstay of treatment for many cases of eosinophilic pneumonia, particularly for acute and chronic eosinophilic pneumonias 3, 4, 5.
  • The cessation of exposure to the inciting agent, such as smoking, is also an essential part of treatment 5.
  • The prognosis for eosinophilic pneumonia is generally excellent if treatment is initiated in a timely manner 3, 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Eosinophilic Pneumonias.

The journal of allergy and clinical immunology. In practice, 2018

Research

Pulmonary eosinophilia.

Clinical reviews in allergy & immunology, 2008

Research

Acute Eosinophilic Pneumonia. Causes, Diagnosis, and Management.

American journal of respiratory and critical care medicine, 2018

Research

Acute eosinophilic pneumonia: radiographic and CT findings in six patients.

AJR. American journal of roentgenology, 1996

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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