Storage Requirements for Testosterone Cypionate Before Opening
Testosterone cypionate does NOT require refrigeration before opening and should be stored at controlled room temperature of 20°-25°C (68°-77°F), protected from light. 1
FDA-Approved Storage Guidelines
The FDA drug label explicitly states storage requirements for unopened testosterone cypionate vials:
- Store at 20°-25°C (68°-77°F) per USP Controlled Room Temperature specifications 1
- Protect from light at all times 1
- Do not refrigerate - refrigeration is not mentioned as a requirement or recommendation in the official labeling 1
Stability at Room Temperature
Testosterone cypionate formulated in cottonseed oil with benzyl benzoate and benzyl alcohol as preservative remains stable at room temperature until the manufacturer's expiration date when stored properly 1. The oil-based vehicle provides stability without requiring cold storage 1.
Common Storage Pitfalls to Avoid
- Avoid refrigeration: Unlike some injectable medications, testosterone cypionate should not be refrigerated as this may cause the oil-based solution to become more viscous and difficult to draw 1
- Protect from direct sunlight and heat sources: Store in a cool, dry place away from windows and heating elements 1
- Do not freeze: Freezing can alter the formulation and should be avoided 1
- Keep away from excessive heat: Temperatures above 25°C (77°F) for prolonged periods may affect stability 1
After Opening
Once opened, the multiple-dose vial should continue to be stored at controlled room temperature (20°-25°C) and protected from light, following the same storage conditions as unopened vials 1. The benzyl alcohol preservative maintains sterility in the multi-dose vial after opening 1.