Should an Ambu (Artificial Manual Breathing Unit) bag be connected to an oxygen tank during positive pressure ventilation?

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Last updated: December 19, 2025View editorial policy

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Should You Connect an Ambu Bag to an Oxygen Tank?

Yes, you should connect an Ambu bag (bag-mask device) to an oxygen tank to deliver the maximal feasible inspired oxygen concentration during positive pressure ventilation, particularly during resuscitation and emergency situations. 1

Primary Recommendation for Oxygen Supplementation

  • During CPR and resuscitation, use 100% inspired oxygen (FiO₂ 1.0) as soon as it becomes available, as this optimizes arterial oxyhemoglobin content and oxygen delivery to vital organs. 1

  • The American Heart Association recommends using maximal feasible inspired oxygen concentration during CPR when supplementary oxygen is available. 1

  • Empirical use of 100% oxygen during brief periods of CPR is reasonable and does not cause clinically significant toxicity during the short duration of resuscitation efforts. 1

Optimal Oxygen Delivery Setup

To achieve near 100% oxygen delivery, you need proper equipment configuration:

  • Connect oxygen at 10-15 L/min flow rate to the bag-mask device's oxygen inlet port. 2

  • Use a reservoir attachment (2.5-L bag reservoir or demand valve) to consistently deliver FiO₂ of 1.0 (100% oxygen). 3

  • Without a reservoir, bag-mask devices deliver significantly lower oxygen concentrations even with supplemental oxygen flow. 3

  • Corrugated tube reservoirs should NOT be used as they are highly sensitive to variations in ventilatory technique and cannot reliably deliver consistent oxygen concentrations. 3

Critical Technical Considerations

Proper two-person technique maximizes effectiveness:

  • Use two trained providers when possible—one to maintain mask seal and airway patency, the other to squeeze the bag. 1, 2

  • Deliver 600 mL tidal volume over 1 second, sufficient to produce visible chest rise without excessive pressure. 1, 2

  • During CPR without an advanced airway, deliver 2 breaths during pauses after every 30 compressions. 1

Device Performance Variations

Not all self-inflating bags perform equally:

  • Research demonstrates large variations in oxygen delivery between different bag-mask models, with some delivering as low as 39% oxygen despite 15 L/min oxygen flow, while others achieve 99.5%. 4

  • Four out of six commonly tested models (Ambu and Laerdal brands) delivered high oxygen fractions, while two models (Intersurgical and O-Two) significantly underperformed. 4

  • This variability poses a serious threat to patient safety, particularly during resuscitation and emergency anesthesia. 4

Critical Pitfalls to Avoid

Excessive ventilation causes significant harm:

  • Avoid hyperventilation—excessive rate or volume increases intrathoracic pressure, reduces venous return and cardiac output, and increases aspiration risk. 2

  • Use only enough force to produce chest rise—excessive pressure causes gastric insufflation, gastric distension, diaphragm elevation, and aspiration. 2

  • Single-provider bag-mask ventilation during CPR is not recommended—use mouth-to-mask ventilation instead if alone. 2

Special Populations

For neonatal resuscitation:

  • Self-inflating bags can deliver titrated oxygen concentrations (21%-100%) by adjusting oxygen flow rates from 0.25 L/min to 5 L/min, useful in resource-limited settings without blenders. 5

  • With 5 L/min oxygen flow, all self-inflating bags deliver close to 100% oxygen regardless of peak inspiratory pressure. 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Bag-Mask Ventilation After Pre-Oxygenation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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