From the Guidelines
Delayed pressure urticaria is the diagnosis for pressure urticaria.
Key Characteristics
- The weals of physical urticaria, including delayed pressure urticaria, usually last less than 1 h, except for delayed pressure urticaria which takes 2-6 h to develop and up to 48 h to fade 1
- Delayed pressure urticaria is a type of physical urticaria that is triggered by mechanical stimuli, specifically pressure 1
- It is characterized by swellings that are induced rather than spontaneous and can be distinguished from other types of urticaria by its unique duration and triggers 1
- The diagnosis of delayed pressure urticaria can be made based on the clinical presentation and duration of individual weals, without extensive investigation 1
- It is essential to distinguish delayed pressure urticaria from other types of urticaria, such as urticarial vasculitis, which presents with small vessel vasculitis histologically and may have joint and renal involvement 1
From the Research
Diagnosis of Pressure Urticaria
The diagnosis of pressure urticaria can be made through a combination of clinical evaluation and diagnostic tests.
- A thorough history taking is essential to identify the association between pressure-related symptoms and the preceding physical stimulus 2.
- Pressure challenge tests, such as the dermographometer test or the weighted rod test, can be used to diagnose delayed pressure urticaria (DPU) 2, 3.
- Skin biopsy may also be performed to confirm the diagnosis, with characteristic findings including deep dermal inflammatory infiltrate of neutrophils and eosinophils 4, 3.
- The autologous serum skin test may also be positive in some cases of DPU 3.
Diagnostic Criteria
The diagnostic criteria for pressure urticaria include:
- The development of deep swellings at sites of pressure application on the skin 5.
- A delay of several hours between the application of pressure and the appearance of symptoms 4.
- The presence of erythematous, often painful swellings at sites of sustained pressure on the skin 4.
- Resistance to antihistamines and other non-steroidal medications 3.
Incidence and Prevalence
Pressure urticaria is a relatively rare condition, with an estimated incidence of 22% in patients with chronic urticaria 2.