From the Guidelines
The current evidence suggests that implant contraceptives do not significantly increase the risk of breast cancer, and their use can be considered safe in terms of breast cancer risk. The most recent and highest quality study, 1, found that the relative risk for breast cancer among women who had used oral contraceptives or DMPA when they were aged ≥40 years compared with those who had never used either method was small but nonsignificant. This study, published in 2024, provides the most up-to-date evidence on the topic.
Key Points to Consider
- The safety profile of implant contraceptives regarding breast cancer risk is reassuring because they contain only progestin (etonogestrel) without estrogen, which is thought to play a more significant role in hormone-sensitive cancers 1.
- Women with a personal history of breast cancer should generally avoid hormonal contraceptives, including implants, and should discuss non-hormonal options with their healthcare provider 1.
- Those with a strong family history of breast cancer but no personal history can typically use implants safely.
- Regular breast cancer screening according to age-appropriate guidelines remains important for all women regardless of contraceptive choice.
- Any new breast symptoms should prompt medical evaluation, even while using implant contraception.
Important Considerations for Healthcare Providers
- When considering the use of implant contraceptives in women with a history of breast cancer or those at high risk for breast cancer, healthcare providers should weigh the benefits and risks of hormonal contraception and discuss non-hormonal options with their patients 1.
- The use of implant contraceptives should be individualized based on a woman's medical history, risk factors, and personal preferences.
- Healthcare providers should also consider the risks associated with continuing contraception, including the risk of acute cardiovascular events and breast cancer, and discuss these risks with their patients 1.
From the Research
Breast Cancer in Implant Contraceptive Users
- There is no direct evidence in the provided studies regarding the relationship between breast cancer and implant contraceptive users.
- The studies focus on breast cancer screening, prevention, and risk assessment, but do not mention implant contraceptives as a factor.
- Studies such as 2, 3, 4, 5, 6 discuss various aspects of breast cancer, including screening methods, risk assessment tools, and preventive therapies, but do not address the specific topic of implant contraceptives and breast cancer.
Related Factors
- Some studies mention the importance of considering reproductive and lifestyle factors in breast cancer risk assessment 3.
- However, these studies do not specifically discuss implant contraceptives as a factor.
- The studies emphasize the need for personalized and multidisciplinary approaches to breast cancer prevention, particularly for high-risk women 3, 6.