Diagnostic Evaluation for Adult ADHD
When an adult presents with suspected ADHD, you must conduct a comprehensive psychiatric evaluation that documents childhood onset of symptoms (before age 12), current symptom burden (at least 5 symptoms in either domain persisting ≥6 months), and cross-situational functional impairment in at least 2 settings, supplemented by validated rating scales, collateral information, and systematic screening for mimicking conditions and comorbidities. 1
Required Documentation Components
1. Childhood Onset Verification
- Document that ADHD symptoms were present before age 12 years as mandated by DSM-5 criteria 1, 2
- Obtain collateral information from family members, old school records, or report cards to corroborate childhood symptoms 1, 3
- Use the Wender Utah Rating Scale to systematically assess retrospective childhood symptoms 1
2. Current Symptom Assessment
- Document at least 5 symptoms of inattention and/or hyperactivity-impulsivity that have persisted for at least 6 months in adults (note this differs from the 6-symptom threshold in children) 1
- Administer the Adult ADHD Self-Report Scale (ASRS-V1.1) as your primary screening tool—a positive screen requires endorsing "often" or "very often" for 4 or more of 6 questions 1, 4
- Consider the Conners Adult ADHD Rating Scale (CAARS) as an alternative validated instrument 1, 4
3. Cross-Situational Impairment Documentation
- Verify functional impairment in at least 2 settings such as work, home, or social relationships through direct questioning and collateral sources 1, 2
- Document specific examples of how symptoms cause clinically significant impairment in occupational, academic, or social functioning 1, 2
Medical Screening Requirements
Rule Out Medical Mimics
- Perform a focused medical assessment to exclude conditions that mimic ADHD 1
- Consider thyroid function tests to rule out thyroid disorders 1
- Screen for sleep disorders (especially restless leg syndrome and hypersomnolence, which share pathophysiological mechanisms with ADHD) 1, 5
- Evaluate for neurological conditions through history and examination 1
Mandatory Comorbidity Screening
Psychiatric Differential Diagnosis
- Systematically screen for mood disorders (bipolar disorder and major depression) that can mimic ADHD symptoms 1, 4
- Evaluate for anxiety disorders (generalized anxiety, social phobia) which overlap substantially with ADHD presentation 1, 4
- Screen for substance use disorders, which occur in 80% of adults with ADHD either as self-medication attempts or due to impulsivity 1, 5
- Assess for personality disorders, particularly borderline and antisocial personality disorder 1, 5
Why This Matters
- ADHD is comorbid with other psychiatric conditions in 80% of adult cases, making differential diagnosis critical 5
- Comorbid conditions alter treatment approach and must be identified before initiating therapy 1
Diagnostic Algorithm
Follow this step-by-step approach:
- Initial Screening: Administer ASRS-V1.1 1, 4
- Comprehensive Clinical Interview: Document childhood onset, current symptoms, and functional impairment 1, 3
- Collateral Information: Obtain information from family members or review old records 1, 3
- Structured Rating Scales: Complete ASRS-V1.1 or CAARS and Wender Utah Rating Scale 1, 4
- Comorbidity Screening: Systematically evaluate for mood, anxiety, substance use, and personality disorders 1, 5
- Medical Screening: Rule out thyroid disorders, sleep disorders, and neurological conditions 1
- Functional Impairment Assessment: Document impairment in at least 2 settings 1, 2
Critical Pitfalls to Avoid
- Do not rely solely on rating scale scores—they systematically collect information but cannot diagnose ADHD without comprehensive clinical evaluation 1, 6
- Do not skip collateral information gathering—self-awareness of ADHD symptoms can be difficult for adults who have lived with them since childhood 3
- Do not miss comorbid conditions—failure to screen for anxiety, depression, and substance use will lead to treatment failure 1, 5
- Do not diagnose ADHD when symptoms are better explained by another psychiatric disorder—the substantial symptom overlap requires careful differential diagnosis 4, 5
When to Refer
Consider referral to psychiatry or psychology when:
- Diagnostic uncertainty persists after initial evaluation 1
- Complex comorbid psychiatric conditions are present that require specialized management 1
- Specialized treatment such as cognitive-behavioral therapy or cognitive remediation is needed 1, 5
Adult-Specific Considerations
- In adults, hyperactivity is often internalized rather than externally observable 5
- Inattention symptoms may be masked by anxiety or obsessive-like compensation strategies 5
- Adults often present with emotional dysregulation and executive function deficits beyond core ADHD symptoms 5, 7
- The diagnostic interview should specifically probe for disorganization, poor time management, and procrastination as associated features 7