What is the management for a patient in ventricular tachycardia (Vtach) cardiac arrest?

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Last updated: December 21, 2025View editorial policy

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Management of Ventricular Tachycardia Cardiac Arrest

Pulseless ventricular tachycardia is treated identically to ventricular fibrillation with immediate unsynchronized high-energy defibrillation followed by CPR, not synchronized cardioversion. 1

Immediate Recognition and Initial Response

  • Confirm pulselessness immediately – pulseless VT is a cardiac arrest rhythm requiring defibrillation, not cardioversion 1, 2
  • Activate the response team capable of identifying the mechanism and carrying out prompt intervention 1
  • Begin high-quality CPR immediately if a defibrillator is not immediately available 1
  • Do not use synchronized cardioversion for pulseless VT, as the device may not sense a QRS wave and shock delivery may fail 1

Defibrillation Strategy

Deliver unsynchronized high-energy shocks (defibrillation doses) as soon as the defibrillator is available:

  • Use biphasic waveform defibrillators with initial energy of 200J for biphasic devices 1
  • If using monophasic waveforms, start at 360J 1
  • Minimize pre-shock and peri-shock pauses – charge the defibrillator during chest compressions to maximize chest compression fraction 3
  • Deliver a single shock followed by immediate resumption of CPR for 2 minutes before rhythm check 1
  • Do not deliver 3-shock sequences; single shocks with immediate CPR have replaced this outdated approach 1

Critical timing considerations:

  • If the arrest is witnessed and a defibrillator is immediately available, defibrillate without delay 3
  • If there will be any delay in obtaining the defibrillator, perform CPR while the device is being obtained 3
  • Shorter pre-shock pauses are associated with higher survival rates 3

Post-Shock CPR Protocol

  • Resume chest compressions immediately after shock delivery without pausing to check rhythm or pulse 1
  • Continue high-quality CPR for 2 minutes (5 cycles) before the next rhythm check 1
  • Coordinate CPR with defibrillation to minimize interruptions in chest compressions 1

Medication Administration

After the first shock and during CPR:

  • Establish IV or IO access without interrupting chest compressions 1
  • Administer epinephrine 1 mg IV every 3-5 minutes 1
  • Consider amiodarone 300 mg IV bolus for refractory VF/pulseless VT after the first shock 1, 4
  • Amiodarone is FDA-approved for frequently recurring VF and hemodynamically unstable VT refractory to other therapy 4
  • A second dose of amiodarone 150 mg IV may be given for recurrent or refractory VF/pulseless VT 4
  • Lidocaine 1-1.5 mg/kg IV may be considered if amiodarone is unavailable or contraindicated 1

Refractory VF/Pulseless VT Management

If the rhythm remains VF/pulseless VT after 3 or more defibrillation attempts:

  • Continue the defibrillation-CPR-epinephrine cycle 1
  • Ensure adequate amiodarone dosing has been administered 4
  • Consider double defibrillation (dual sequential external defibrillation) using two biphasic defibrillators with pads in anterolateral and anterior-posterior configurations 3
  • Verify correct pad placement and consider changing pad position if initial attempts fail 1
  • Recurrent VF is common (48% within 2 minutes, 74% during prehospital care), and repeated shocks may be necessary 5

Airway Management

  • Intubate the patient during CPR without causing undue delay in chest compressions or defibrillation 1
  • Neither intubation nor IV access should delay defibrillation attempts 1

Reversible Causes

Evaluate and correct potential reversible causes during CPR cycles:

  • Correct electrolyte imbalances, particularly hypokalemia and hypomagnesemia 1
  • Assess for acute myocardial ischemia – consider emergent coronary angiography in appropriate candidates 1
  • Rule out hypoxia, acidosis, hypothermia, and toxins 2

Post-Resuscitation Care

If return of spontaneous circulation is achieved:

  • Direct admission to the catheterization laboratory is recommended for comatose survivors with STEMI criteria on post-resuscitation ECG 1
  • Consider coronary angiography within 2 hours for comatose survivors without ST-elevation, particularly if hemodynamically unstable 1
  • Initiate beta-blocker therapy during hospital stay and continue thereafter in all patients without contraindications 1
  • Consider ICD implantation for secondary prevention after stabilization 1

Common Pitfalls to Avoid

  • Never use synchronized cardioversion for pulseless VT – this is a fatal error as the device may fail to deliver a shock 1
  • Do not delay defibrillation to establish IV access or intubate 1
  • Avoid prolonged pulse checks or rhythm analysis that interrupt chest compressions 1, 3
  • Do not use prophylactic antiarrhythmic drugs other than beta-blockers, as they may be harmful 1
  • Do not abandon resuscitation while the rhythm remains VF/pulseless VT – recurrent VF is common and shocks that terminate later episodes increasingly result in sustained organized rhythms 1, 5
  • Avoid using drop counter infusion sets for amiodarone, as they may underdose by up to 30%; use volumetric infusion pumps 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Immediate Treatment for Ventricular Tachycardia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Emergency medicine updates: Defibrillation strategies in cardiac arrest.

The American journal of emergency medicine, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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