Management of Ventricular Tachycardia Cardiac Arrest
Pulseless ventricular tachycardia is treated identically to ventricular fibrillation with immediate unsynchronized high-energy defibrillation followed by CPR, not synchronized cardioversion. 1
Immediate Recognition and Initial Response
- Confirm pulselessness immediately – pulseless VT is a cardiac arrest rhythm requiring defibrillation, not cardioversion 1, 2
- Activate the response team capable of identifying the mechanism and carrying out prompt intervention 1
- Begin high-quality CPR immediately if a defibrillator is not immediately available 1
- Do not use synchronized cardioversion for pulseless VT, as the device may not sense a QRS wave and shock delivery may fail 1
Defibrillation Strategy
Deliver unsynchronized high-energy shocks (defibrillation doses) as soon as the defibrillator is available:
- Use biphasic waveform defibrillators with initial energy of 200J for biphasic devices 1
- If using monophasic waveforms, start at 360J 1
- Minimize pre-shock and peri-shock pauses – charge the defibrillator during chest compressions to maximize chest compression fraction 3
- Deliver a single shock followed by immediate resumption of CPR for 2 minutes before rhythm check 1
- Do not deliver 3-shock sequences; single shocks with immediate CPR have replaced this outdated approach 1
Critical timing considerations:
- If the arrest is witnessed and a defibrillator is immediately available, defibrillate without delay 3
- If there will be any delay in obtaining the defibrillator, perform CPR while the device is being obtained 3
- Shorter pre-shock pauses are associated with higher survival rates 3
Post-Shock CPR Protocol
- Resume chest compressions immediately after shock delivery without pausing to check rhythm or pulse 1
- Continue high-quality CPR for 2 minutes (5 cycles) before the next rhythm check 1
- Coordinate CPR with defibrillation to minimize interruptions in chest compressions 1
Medication Administration
After the first shock and during CPR:
- Establish IV or IO access without interrupting chest compressions 1
- Administer epinephrine 1 mg IV every 3-5 minutes 1
- Consider amiodarone 300 mg IV bolus for refractory VF/pulseless VT after the first shock 1, 4
- Amiodarone is FDA-approved for frequently recurring VF and hemodynamically unstable VT refractory to other therapy 4
- A second dose of amiodarone 150 mg IV may be given for recurrent or refractory VF/pulseless VT 4
- Lidocaine 1-1.5 mg/kg IV may be considered if amiodarone is unavailable or contraindicated 1
Refractory VF/Pulseless VT Management
If the rhythm remains VF/pulseless VT after 3 or more defibrillation attempts:
- Continue the defibrillation-CPR-epinephrine cycle 1
- Ensure adequate amiodarone dosing has been administered 4
- Consider double defibrillation (dual sequential external defibrillation) using two biphasic defibrillators with pads in anterolateral and anterior-posterior configurations 3
- Verify correct pad placement and consider changing pad position if initial attempts fail 1
- Recurrent VF is common (48% within 2 minutes, 74% during prehospital care), and repeated shocks may be necessary 5
Airway Management
- Intubate the patient during CPR without causing undue delay in chest compressions or defibrillation 1
- Neither intubation nor IV access should delay defibrillation attempts 1
Reversible Causes
Evaluate and correct potential reversible causes during CPR cycles:
- Correct electrolyte imbalances, particularly hypokalemia and hypomagnesemia 1
- Assess for acute myocardial ischemia – consider emergent coronary angiography in appropriate candidates 1
- Rule out hypoxia, acidosis, hypothermia, and toxins 2
Post-Resuscitation Care
If return of spontaneous circulation is achieved:
- Direct admission to the catheterization laboratory is recommended for comatose survivors with STEMI criteria on post-resuscitation ECG 1
- Consider coronary angiography within 2 hours for comatose survivors without ST-elevation, particularly if hemodynamically unstable 1
- Initiate beta-blocker therapy during hospital stay and continue thereafter in all patients without contraindications 1
- Consider ICD implantation for secondary prevention after stabilization 1
Common Pitfalls to Avoid
- Never use synchronized cardioversion for pulseless VT – this is a fatal error as the device may fail to deliver a shock 1
- Do not delay defibrillation to establish IV access or intubate 1
- Avoid prolonged pulse checks or rhythm analysis that interrupt chest compressions 1, 3
- Do not use prophylactic antiarrhythmic drugs other than beta-blockers, as they may be harmful 1
- Do not abandon resuscitation while the rhythm remains VF/pulseless VT – recurrent VF is common and shocks that terminate later episodes increasingly result in sustained organized rhythms 1, 5
- Avoid using drop counter infusion sets for amiodarone, as they may underdose by up to 30%; use volumetric infusion pumps 4