What is Melasma (Mask of Pregnancy) treatment with oral medications?

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From the Research

There is no specific medication called the "Malasma Pill." Melasma is a common skin condition characterized by brown or gray-brown patches on the face, particularly on the cheeks, forehead, nose, and upper lip. Treatment for melasma typically involves a combination approach rather than a single pill.

Common Treatments

The most common treatments include:

  • Topical medications containing hydroquinone, tretinoin, corticosteroids, or combinations like the triple cream (containing hydroquinone, tretinoin, and a corticosteroid) 1
  • Oral medications sometimes used include tranexamic acid tablets (500-1000mg daily, divided into 2-3 doses for several months) which can help reduce melanin production 2

Sun Protection

Sun protection is absolutely essential in managing melasma, as UV exposure worsens the condition. This includes:

  • Daily use of broad-spectrum SPF 30+ sunscreen
  • Wearing wide-brimmed hats
  • Avoiding peak sun hours Melasma occurs due to overproduction of melanin by melanocytes, often triggered by hormonal changes (pregnancy, birth control pills), sun exposure, or genetic factors, which explains why a comprehensive approach rather than a single pill is needed for management 3, 4, 5

References

Research

Melasma Treatment: An Evidence-Based Review.

American journal of clinical dermatology, 2020

Research

Melasma: an Up-to-Date Comprehensive Review.

Dermatology and therapy, 2017

Research

Oral Tranexamic Acid for the Treatment of Melasma: A Review.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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