How to Run a Code Blue
Immediately begin high-quality chest compressions at 100-120 per minute with a depth of 2-2.4 inches, establish clear team roles with a designated leader, and follow a systematic ACLS algorithm approach while minimizing interruptions to compressions. 1, 2
Initial Response and Team Activation
Verify scene safety before approaching the patient to avoid becoming a second victim. 2 Check for responsiveness by shouting and tapping the victim, then simultaneously assess breathing and pulse within 10 seconds—look for no breathing or only gasping while checking for a pulse. 3, 2
Activate the emergency response system immediately by calling a "code blue" to mobilize all necessary responders simultaneously, which saves time and prevents confusion. 3 In the current era of mobile devices, both the call to activate the emergency response and initiation of CPR should occur simultaneously. 3
Immediate CPR Initiation
Start chest compressions immediately without removing the patient's clothing first. 3 A lone healthcare provider should commence with chest compressions rather than ventilation to minimize time to first compression. 3
Compression Technique
- Push hard and fast: Compress at least 2 inches (5-6 cm) in adults at a rate of 100-120 compressions per minute 1, 2
- Allow complete chest recoil between compressions—incomplete recoil prevents full cardiac refilling and is a critical error 1, 2
- Minimize interruptions in chest compressions, maintaining a chest compression fraction >80% 1
- Use a 30:2 compression-to-ventilation ratio until an advanced airway is placed 3, 1
Team Role Assignment
Assign specific roles immediately to prevent too many people attending without assigned tasks, which hinders team performance: 1, 4
- Designated team leader (identifiable leadership is critical) 4
- Compressor (rotate every 2 minutes to prevent fatigue) 1
- Airway manager (respiratory therapist positioned at head of bed) 1
- Medication administrator 1
- Defibrillator operator 1
- Recorder/documentation 1
Airway Management Algorithm
Start with two-handed bag-mask ventilation using 100% oxygen at ≥15 L/min as first-line airway management, which is more effective than single-handed technique. 3, 1 For first responders with minimal airway experience, bag-mask ventilation is the most rapid noninvasive strategy. 3
Stepwise Airway Approach
Limit each technique to 2 attempts maximum to minimize compression interruptions: 3, 1
- First intubation attempt (use 6.0-7.0 mm inner diameter endotracheal tube) 3
- Second intubation attempt (if first fails) 3
- First supraglottic airway attempt (if intubation fails) 3
- Second supraglottic airway attempt (if first fails) 3
- Return to mask ventilation (if supraglottic fails) 3
- Cricothyrotomy (if mask ventilation inadequate) 3
Do not attempt intubation for >30 seconds as prolonged attempts interrupt compressions and decrease survival. 1
Post-Intubation Management
Once an advanced airway is placed:
- Ventilate at 8-10 breaths per minute with continuous compressions (no pauses for ventilation) 3, 1
- Immediately confirm tube placement with continuous capnography 3, 1
- Monitor end-tidal CO2 to confirm adequate tube placement and perfusion 1
- Avoid hyperventilation (>10 breaths/min), which decreases survival by reducing venous return and cardiac output 3, 1
Rhythm Analysis and Defibrillation
Charge the defibrillator during compressions to minimize hands-off time, then deliver shock immediately after a brief pause. 1 Use the AED/defibrillator as soon as it becomes available. 3, 2, 5
- Check rhythm every 2 minutes during CPR 2
- Announce rhythm checks and shock delivery clearly to the team 1
- Resume compressions immediately after shock delivery without performing a pulse check 1, 5
- Deliver one shock for shockable rhythms (ventricular fibrillation or pulseless ventricular tachycardia), then immediately resume CPR for 2 minutes 2, 5
Medication Administration
Administer epinephrine every 3-5 minutes throughout resuscitation for all cardiac arrest rhythms. 1, 2 Consider amiodarone or lidocaine for refractory ventricular fibrillation or pulseless ventricular tachycardia. 2
Critical Pitfalls to Avoid
- Never hyperventilate—this is the most common error reducing survival 1
- Never perform prolonged intubation attempts (>30 seconds) that interrupt compressions 1
- Never lean on the chest between compressions—this prevents adequate cardiac refilling 2
- Never delay CPR to obtain a detailed history or remove clothing 3, 2
- Never perform prolonged pulse checks—if uncertain after 10 seconds, start CPR 2
- Never allow too many people to attend without assigned roles, as this hinders team performance 4
Quality Metrics to Monitor
- Compression depth: 2-2.4 inches 1
- Compression rate: 100-120 per minute 1, 2
- Chest compression fraction: >80% 1
- Ventilation rate post-intubation: 8-10 breaths/min 1
- Use real-time feedback devices during training to ensure quality 1
Post-Resuscitation Care
- Continuously monitor end-tidal CO2 to confirm tube placement and adequate perfusion 1
- Assess chest rise with each ventilation 1
- Secure endotracheal tube and verify position repeatedly, as movement and secretions cause dislodgement 1
- Regularly aspirate airways using sterile technique starting immediately after intubation 1
- Monitor oxygen saturation trends, airway pressures, and tube security continuously 1
Training and Preparedness
Conduct unannounced mock code blues in actual clinical locations to identify system gaps and improve team performance. 1, 6, 7 Use CPR feedback devices during training that provide directive feedback on compression rate, depth, release, and hand position, which significantly improves objective CPR quality metrics, particularly for novice providers. 1 Training has been shown to significantly reduce arrival time, improve recovery time, increase ICU transfers, and decrease mortality. 7