How to Administer a Shoulder Steroid Injection
For shoulder pain, inject 40 mg triamcinolone acetonide intra-articularly into the glenohumeral joint or subacromial space using strict aseptic technique, with ultrasound guidance strongly recommended to ensure accurate placement. 1, 2
Pre-Injection Assessment
- Identify the specific pain source: Determine whether pain originates from the glenohumeral joint (arthritis, capsulitis) or subacromial space (rotator cuff pathology, bursitis) through physical examination and imaging 3, 4
- Use ultrasound or MRI to visualize pathology and guide injection site selection 3
- Verify no contraindications exist, including active infection, tendon rupture risk, or systemic corticosteroid complications 4
Injection Technique
Equipment and Preparation
- Use triamcinolone acetonide 40 mg as the standard dose for shoulder injections 1, 5, 6
- Shake the vial thoroughly before withdrawal to ensure uniform suspension; inspect for clumping or granular appearance (agglomeration) and discard if present 1
- Inject without delay after drawing up medication to prevent settling in the syringe 1
- Employ strict aseptic technique to avoid introducing infection 1
Anatomical Approach
For glenohumeral joint injection:
- Use the posterior approach as the standard technique 6
- Insert needle into the glenohumeral joint space under ultrasound guidance when possible 7, 2
- Accuracy matters significantly: Only 42% of attempted glenohumeral injections without imaging guidance are accurately placed, and accurate placement significantly affects clinical outcomes 2
For subacromial injection:
- Target the subacromial space when pain relates to rotator cuff or bursal inflammation 4
- Use ultrasound guidance to ensure proper needle placement 2
Critical Safety Points
- Never inject directly into tendon substance - only peritendinous injection is acceptable, as intra-tendinous injection inhibits healing, reduces tensile strength, and predisposes to spontaneous rupture 4
- Avoid subcutaneous fat atrophy by ensuring deep, accurate placement 1
- Do not enter blood vessels - aspirate before injecting 1
Dosing Specifics
- Standard dose: 40 mg triamcinolone acetonide for most shoulder conditions 1, 5, 6
- For smaller joints: 5-15 mg; for larger joints like the shoulder: 5-40 mg 1
- 40 mg is superior to 10 mg for symptom relief in frozen shoulder 5
- Maximum of 3 injections spaced 3 weeks apart if initial injection provides insufficient relief 6
- Single injections into multiple joints up to a total of 80 mg have been given safely 1
Post-Injection Management
- Warn patients about post-injection pain flare, which is a recognized complication 3, 4
- Continue physical therapy - the injection facilitates rehabilitation but does not replace it 3, 4
- Monitor for short-term pain relief within 1-3 weeks; long-term pain reduction beyond this period is not well-verified 8, 3
- Expect greater improvement in pain and sleep disturbance than in range of motion 5
Expected Outcomes
- Short-term pain reduction is significant in observational studies for both glenohumeral and subacromial injections 8, 3
- Effectiveness rates of 81-83% have been reported for primary frozen shoulder 6
- Diabetic frozen shoulder responds better to triamcinolone (69% improvement) compared to methylprednisolone (39% improvement) 6
- The effect is primarily on pain relief rather than functional improvement 5, 9
Important Caveats
- Ultrasound guidance dramatically improves accuracy: Without imaging, only 29-42% of injections are accurately placed, and accuracy significantly affects outcomes 2
- Evidence quality is limited: The American Academy of Orthopaedic Surgeons cannot recommend for or against injectable corticosteroids for glenohumeral osteoarthritis due to insufficient high-quality evidence 3, 4
- Long-term efficacy is unproven - benefits are primarily short-term (weeks, not months) 8, 3