Do we need to clamp a Central Venous Catheter (CVC) before removal?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Clamping Central Venous Catheters Before Removal

Yes, you must clamp the central venous catheter before removal to prevent venous air embolism, a potentially fatal complication that can occur at any time during the removal process. 1

Critical Safety Steps for CVC Removal

Mandatory Pre-Removal Positioning and Clamping

  • Position the patient flat or in 5-10 degrees Trendelenburg (head-down position) with the exit site below the level of the heart to reduce the risk of air entrainment into the venous system 1, 2

  • Close the clamp on all CVC lumens before disconnecting or removing the catheter to prevent air from entering through the catheter during removal 1

  • Instruct cooperative patients to perform the Valsalva maneuver during catheter withdrawal to increase intrathoracic pressure and further reduce air embolism risk 2

The Removal Technique

  • Apply firm digital pressure for at least 5 minutes at the exit site immediately after catheter removal, followed by application of an occlusive dressing 1

  • The patient should remain flat during and after the procedure, as air embolism can occur not only during removal but also in the immediate post-removal period 1

Why This Matters: The Air Embolism Risk

Venous air embolism may be fatal and can occur at any time from insertion to removal, with an incidence as high as 0.8%. 1 The evidence demonstrates that:

  • Multiple case reports document serious outcomes including cerebral infarction, cardiovascular collapse, and death from air embolism during CVC removal 3, 4

  • A survey of 140 physicians found that only 26% cited concern for air embolism during CVC removal, and 9% incorrectly elevated the head of the bed during removal—a practice that increases risk 4

  • Paradoxical systemic air embolism can occur in patients with undiagnosed atrial septal defects or other right-to-left shunts, leading to multi-organ damage 3

Common Pitfalls to Avoid

Never elevate the head of the bed during CVC removal, as this creates negative intrathoracic pressure that facilitates air entrainment into the venous system 4

Do not remove the catheter without ensuring the clamps are closed, even if you plan to remove it quickly—air can enter in milliseconds 1

Avoid removing CVCs in hypovolemic patients without first correcting their volume status, as hypovolemia increases negative venous pressure and air embolism risk 2

Special Considerations for Long-Term Catheters

  • Cuffed devices and ports require surgical cut-down for removal due to complex adherent fibrin sleeves and scar tissue formation 1

  • Very long-term catheters may become attached to the superior vena cava or right atrial wall and cannot be removed by traction alone—seek vascular surgery or interventional radiology consultation if difficulties occur 1

  • Persistent bleeding after removal may require a skin stitch, but the occlusive dressing remains essential for air embolism prevention 1

Post-Removal Monitoring

  • Keep the occlusive dressing in place and monitor for signs of air embolism including sudden respiratory distress, cardiovascular collapse, altered mental status, or neurological deficits 1, 3

  • If air embolism is suspected after removal, immediately place the patient in head-down left lateral position and attempt aspiration of air through any remaining venous access 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Massive air embolism while removing a central venous catheter.

International journal of critical illness and injury science, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.