What is the diagnosis (dx) code for benzodiazepine use?

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ICD-10 Diagnosis Codes for Benzodiazepine Use

Based on the clinical context and pattern of use, the appropriate ICD-10 diagnosis codes for benzodiazepine use are:

Primary Diagnostic Codes

For therapeutic/prescribed benzodiazepine use without complications:

  • Z79.4 - Long-term (current) use of insulin (Note: While guidelines reference benzodiazepine use extensively 1, the specific ICD-10 code for therapeutic benzodiazepine use follows the Z-code structure for long-term medication use)

For problematic benzodiazepine use patterns:

Benzodiazepine Use Disorder

  • F13.10 - Sedative, hypnotic, or anxiolytic use disorder, mild (uncomplicated) 2, 3
  • F13.20 - Sedative, hypnotic, or anxiolytic use disorder, moderate or severe (uncomplicated) 2, 4
  • F13.21 - Sedative, hypnotic, or anxiolytic use disorder, moderate or severe, in remission 4, 5

Benzodiazepine Dependence

  • F13.20 - Sedative, hypnotic, or anxiolytic dependence, uncomplicated 2, 3, 5
  • F13.23 - Sedative, hypnotic, or anxiolytic dependence with withdrawal 1, 3, 5
  • F13.239 - Sedative, hypnotic, or anxiolytic dependence with withdrawal, unspecified 3, 5

Benzodiazepine Abuse

  • F13.10 - Sedative, hypnotic, or anxiolytic abuse, uncomplicated 2, 3
  • F13.120 - Sedative, hypnotic, or anxiolytic abuse with intoxication, uncomplicated 2

Benzodiazepine Poisoning/Overdose

  • T42.4X1A - Poisoning by benzodiazepines, accidental (unintentional), initial encounter 1
  • T42.4X2A - Poisoning by benzodiazepines, intentional self-harm, initial encounter 1
  • T42.4X4A - Poisoning by benzodiazepines, undetermined, initial encounter 1

Clinical Context for Code Selection

Distinguish between normal therapeutic use and problematic use:

  • Pharmacologic dependence from legitimate prescribed use (requiring tapering when discontinuing) does not constitute addiction and should be coded as therapeutic use 2, 6
  • True abuse involves intentional misuse, typically as a secondary drug to augment other substances or offset adverse effects of other drugs 2, 3
  • Physical dependence manifesting as withdrawal symptoms upon abrupt discontinuation is a predictable physiological adaptation, not abuse 2, 5

Key clinical indicators for problematic use codes:

  • Use beyond prescribed duration (typically beyond 2-4 weeks for anxiety, beyond 2 weeks for insomnia) 6
  • Dose escalation beyond therapeutic range 6, 3
  • Concurrent substance abuse 2, 3
  • Doctor shopping or obtaining from non-medical sources 2
  • Continued use despite harm 3, 4

Common pitfall: Do not code long-term therapeutic benzodiazepine use for chronic anxiety as "dependence" or "abuse" - approximately one-third of long-term users will experience withdrawal symptoms, but this represents normal physiological dependence, not a use disorder 2, 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Benzodiazepine use, abuse, and dependence.

The Journal of clinical psychiatry, 2005

Research

Benzodiazepine harm: how can it be reduced?

British journal of clinical pharmacology, 2014

Research

Benzodiazepines and Related Sedatives.

The Medical clinics of North America, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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